2-Pyrrolidone

2-Pyrrolidone

SCHEMBL27469715

C=C(C)C(=O)OCCN(CC)CC.O=C1CCCN1

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OR51E2 Q9H255 1/20 0.40
THRB P10828 1/20 0.39
TSHR P16473 5/20 0.38
CHRM2 P08172 3/20 0.36
CHRM4 P08173 2/20 0.36
CHRM5 P08912 2/20 0.36
CHRM1 P11229 2/20 0.36
CHRM3 P20309 2/20 0.36
PARP1 P09874 1/20 0.36
SIGMAR1 Q99720 2/20 0.36
PRCP P42785 1/20 0.36
ALDH1A1 P00352 1/20 0.36
POLB P06746 1/20 0.36
CYP2D6 P10635 3/20 0.35
LMNA P02545 3/20 0.35
CYP1A2 P05177 2/20 0.35
MAOA P21397 1/20 0.35
HTR3A P46098 1/20 0.35
HRH3 Q9Y5N1 1/20 0.35
ABCB11 O95342 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Caprolactam SCHEMBL5610881 0.95 FKBP5 (0.40) OR51E2THRBTSHRCHRM2CHRM4
2-Pyrrolidone SCHEMBL10798360 0.90 CHRM2 (0.33) OR51E2THRBTSHRCHRM2CHRM4
2-Pyrrolidone SCHEMBL867329 0.86 OR51E2 (0.42) OR51E2THRBTSHRCHRM2CHRM4
2-Pyrrolidone SCHEMBL8133376 0.83 OR51E2 (0.47) OR51E2THRBTSHRALDH1A1POLB
2-Pyrrolidone SCHEMBL8168482 0.82 TSHR (0.55) OR51E2THRBTSHRALDH1A1POLB
2-Pyrrolidone SCHEMBL17241782 0.82 OR51E2 (0.46) OR51E2THRBTSHRPARP1ALDH1A1
2-Pyrrolidone SCHEMBL28304483 0.82 OR51E2 (0.46) OR51E2THRBTSHRPARP1ALDH1A1
Caprolactam SCHEMBL6408803 0.82 FKBP5 (0.42) OR51E2THRBTSHRCHRM2CHRM4
SCHEMBL14874 0.81 THRB (0.55) THRBTSHRCHRM2CHRM4CHRM5
SCHEMBL28273630 0.81 THRB (0.55) THRBTSHRCHRM2CHRM4CHRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1193729-C Cosmetic composition containing specific polysaccharide resin OREAL (FR) 2005-03-23 CN disclosed
CN-1165275-C Cosmetic composition containing block copolymer ŷ���Źɷ����޹�˾ 2004-09-08 CN disclosed
CN-1372454-A Cosmetic composition containing specific polysaccharide resin OREAL (FR) 2002-10-02 CN disclosed
CN-1341010-A Cosmetic composition containing block copolymer OREAL (FR) 2002-03-20 CN disclosed