Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | GCGR | P47871 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMO | Q99835 | 4/20 | 0.35 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27555435 | 0.94 | RAB9A (0.41) | RAB9AALDH1A1NPC1LMNAHPGD | |
| SCHEMBL27488605 | 0.86 | NPBWR1 (0.36) | ALDH1A1HPGDTSHRMEN1KMT2A | |
| SCHEMBL27471084 | 0.86 | SMN1; SMN2 (0.39) | RAB9AALDH1A1NPC1LMNAHPGD | |
| SCHEMBL27488957 | 0.85 | SMN1; SMN2 (0.40) | RAB9AALDH1A1NPC1LMNAHPGD | |
| SCHEMBL4188310 | 0.83 | PTGS2 (0.50) | RAB9AALDH1A1NPC1LMNAHPGD | |
| SCHEMBL27486810 | 0.83 | RAB9A (0.42) | RAB9ANPC1LMNASMN1; SMN2KMT2A | |
| SCHEMBL4180316 | 0.82 | CA1 (0.46) | RAB9AALDH1A1NPC1LMNAHPGD | |
| SCHEMBL27487895 | 0.81 | MEN1 (0.42) | RAB9AALDH1A1NPC1LMNAHPGD | |
| SCHEMBL27471546 | 0.81 | SMN1; SMN2 (0.45) | RAB9AALDH1A1NPC1LMNAHPGD | |
| SCHEMBL27487167 | 0.80 | NPBWR1 (0.40) | RAB9AALDH1A1NPC1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1167687-C | Arylpyridazinones as prostaglandin endoperoxide H synthase biosynthesis inhibitors | ���Ͽع�����˾ | 2004-09-22 | — | — | CN | disclosed |
| CN-1277605-A | Arylpyridazinones as prostaglandin endoperoxide H synthase biosynthesis inhibitors | ABBOTT LAB (US) | 2000-12-20 | — | — | CN | disclosed |