Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 3/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 6/20 | 0.35 |
| ▸ | TDO2 | P48775 | 6/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.33 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.32 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27486810 | 0.88 | RAB9A (0.42) | NPBWR1MCHR1MAPTKMT2ATRPC5 | |
| SCHEMBL27470577 | 0.86 | RAB9A (0.43) | NPBWR1MCHR1ALDH1A1HPGDCYP1A2 | |
| SCHEMBL4191773 | 0.86 | ALDH1A1 (0.35) | ALDH1A1ESR1POLBHPGDIDO1 | |
| SCHEMBL4189784 | 0.85 | PTGS2 (0.46) | IDO1TDO2 | |
| SCHEMBL4186306 | 0.84 | PTGS2 (0.45) | — | |
| SCHEMBL27487528 | 0.84 | SMN1; SMN2 (0.38) | NPBWR1MCHR1ALDH1A1ESR1POLB | |
| SCHEMBL27471545 | 0.83 | IDO1 (0.38) | NPBWR1MCHR1ALDH1A1ESR1POLB | |
| SCHEMBL27549347 | 0.82 | RAB9A (0.40) | NPBWR1MCHR1MAPTKMT2ATRPC5 | |
| SCHEMBL4180594 | 0.82 | AR (0.36) | ALDH1A1ESR1POLBHPGDIDO1 | |
| SCHEMBL27555435 | 0.81 | RAB9A (0.41) | NPBWR1MCHR1ALDH1A1HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1167687-C | Arylpyridazinones as prostaglandin endoperoxide H synthase biosynthesis inhibitors | ���Ͽع�����˾ | 2004-09-22 | — | — | CN | disclosed |
| CN-1277605-A | Arylpyridazinones as prostaglandin endoperoxide H synthase biosynthesis inhibitors | ABBOTT LAB (US) | 2000-12-20 | — | — | CN | disclosed |