Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LHCGR | P22888 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27514877 | 0.90 | MAPT (0.43) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL27476288 | 0.89 | MAPT (0.42) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL6218802 | 0.87 | ALDH1A1 (0.58) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL27474346 | 0.84 | LHCGR (0.52) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL6216455 | 0.83 | LHCGR (0.59) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL6215602 | 0.81 | ABCB1 (0.53) | MAPTALDH1A1KDM4EHTTTSHR | |
| SCHEMBL6217115 | 0.81 | ALDH1A1 (0.54) | MAPTALDH1A1KDM4EKMT2ALHCGR | |
| SCHEMBL27663684 | 0.79 | MAPT (0.63) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL6217994 | 0.79 | MEN1 (0.53) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL6214865 | 0.79 | LHCGR (0.60) | MAPTALDH1A1KDM4ETDP1LHCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1177848-C | Bicyclic heteroaromatic compounds useful as LH agonists | ��˹��ŵ�� | 2004-12-01 | — | — | CN | disclosed |
| CN-1349535-A | Bicyclic heteroaromatic compounds useful as LH agonists | AKZO NOBEL NV (NL) | 2002-05-15 | — | — | CN | disclosed |