Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ME3 | Q16798 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.42 |
| ▸ | ME2 | P23368 | 3/20 | 0.41 |
| ▸ | ME1 | P48163 | 3/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13279486 | 0.86 | ME2 (0.43) | ME3DRD4ME2ME1KCNH2 | |
| SCHEMBL13279655 | 0.84 | CYP3A4 (0.51) | ME3ME2ME1GAAKDM4E | |
| SCHEMBL5543887 | 0.81 | ME3 (0.48) | ME3L3MBTL1DRD4ME2ME1 | |
| SCHEMBL13282009 | 0.80 | CHRM4 (0.46) | CHRM2KCNH2 | |
| SCHEMBL5547171 | 0.79 | KDM4E (0.45) | ME3DRD4OPRD1DRD3GAA | |
| SCHEMBL27459569 | 0.77 | ESR2 (0.47) | KDM4E | |
| SCHEMBL27622558 | 0.77 | OPRM1 (0.49) | L3MBTL1OPRD1CHRM2HTR1AADRA2A | |
| SCHEMBL13800059 | 0.76 | OPRM1 (0.49) | DRD4OPRD1CHRM2HTR1AADRA2A | |
| SCHEMBL7891539 | 0.74 | MCHR1 (0.56) | ME3DRD4ME2ME1SLC6A2 | |
| SCHEMBL5539933 | 0.74 | KDM4E (0.49) | ME3L3MBTL1DRD4DRD3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1141936-C | Usage of aryl-cyclohexylamine derivant in anti-disturbance of central nervous system | - | 2004-03-17 | — | — | CN | disclosed |
| CN-1248439-A | Usage of aryl-cyclohexylamine derivant in anti-disturbance of central nervous system | HOFFMAN LA ROCHE & CO AKTEINGE (DE) | 2000-03-29 | — | — | CN | disclosed |