Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | NOTUM | Q6P988 | 5/20 | 0.58 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | GUSB | P08236 | 1/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31413771 | 1.00 | ALDH1A1 (0.65) | ALDH1A1LMNANOTUMPTK2TSHR | |
| SCHEMBL3822281 | 0.84 | NOTUM (0.65) | ALDH1A1LMNANOTUMPTK2TSHR | |
| SCHEMBL30566753 | 0.82 | ALDH1A1 (0.67) | ALDH1A1LMNANOTUMPTK2TSHR | |
| SCHEMBL1545045 | 0.82 | ALDH1A1 (0.67) | ALDH1A1LMNANOTUMPTK2TSHR | |
| SCHEMBL30566768 | 0.81 | LMNA (0.65) | ALDH1A1LMNANOTUMTSHRPOLB | |
| SCHEMBL30566766 | 0.81 | ALDH1A1 (0.65) | ALDH1A1LMNANOTUMPTK2TSHR | |
| SCHEMBL30566780 | 0.81 | ALDH1A1 (0.65) | ALDH1A1LMNANOTUMPTK2TSHR | |
| SCHEMBL1544503 | 0.81 | LMNA (0.65) | ALDH1A1LMNANOTUMTSHRPOLB | |
| SCHEMBL29077294 | 0.81 | ALDH1A1 (0.65) | ALDH1A1LMNANOTUMPTK2TSHR | |
| SCHEMBL28531936 | 0.81 | LMNA (0.65) | ALDH1A1LMNANOTUMTSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103288817-A | Schiff base ramification based on 1,3,4-thiadiazole and 1,3,4-oxadiazole as well as preparation method and application thereof | UNIV TIANJIN TECHNOLOGY | 2013-09-11 | — | — | CN | claimed |
| US-20240300932-A1 | N-PHENYLIMINE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF | GUIZHOU UNIVERSITY (CN) | 2024-09-12 | — | — | US | disclosed |
| WO-2024174317-A1 | N-PHENYLIMINE-CONTAINING DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | 贵州大学 | 2024-08-29 | — | — | WO | disclosed |
| CN-116731003-A | N-phenylimine-containing derivative, and preparation method and application thereof | 贵州大学 | 2023-09-12 | — | — | CN | disclosed |
| CN-103288817-A | Schiff base ramification based on 1,3,4-thiadiazole and 1,3,4-oxadiazole as well as preparation method and application thereof | UNIV TIANJIN TECHNOLOGY | 2013-09-11 | — | — | CN | disclosed |
| CN-1177846-C | Oxa(thia)diazolylpyridazinone derivative and its preparing process and application | 华东理工大学 | 2004-12-01 | — | — | CN | disclosed |
| CN-1276373-A | Oxa(thia)diazolylpyridazinone derivative and its preparing process and application | HUADONG SCIENCE & ENGINEERING (CN) | 2000-12-13 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240300932-A1 | N-PHENYLIMINE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF | PNMT, NNMT, PAH | ALDH1A1 780/4885LMNA 2548/4885NOTUM 443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.