Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27510938 | 0.83 | LMNA (0.33) | CYP11B1CYP11B2LMNAKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL27493785 | 0.82 | CYP11B1 (0.38) | CYP11B1CYP11B2LMNAKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL5722667 | 0.82 | PPARG (0.32) | CYP11B1CYP11B2SMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL27477211 | 0.81 | CYP11B1 (0.36) | CYP11B1CYP11B2LMNAKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL27494191 | 0.80 | CYP11B1 (0.36) | CYP11B1CYP11B2LMNAKDM4EALDH1A1 | |
| SCHEMBL27946706 | 0.80 | KDM4E (0.31) | LMNAKDM4EALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27494991 | 0.78 | ALDH1A1 (0.36) | CYP11B1CYP11B2LMNAKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL27493413 | 0.76 | ALDH1A1 (0.33) | ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL8170303 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL27494195 | 0.75 | KCNQ2 (0.32) | KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1191286-C | Ethylene copolymer rubber, process for producing same and use | MITSUI CHEMICALS INC (JP) | 2005-03-02 | — | — | CN | disclosed |
| CN-1344283-A | Ethylene copolymer rubber, process for producing the same, and use thereof | MITSUI CHEMICALS INC (JP) | 2002-04-10 | — | — | CN | disclosed |