Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8170303 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL27493413 | 0.89 | ALDH1A1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL4467654 | 0.87 | MAPT (0.35) | PPARGPPARANPC1MAPTRAB9A | |
| Hydrochloric Acid SCHEMBL27494193 | 0.87 | HTR1A (0.32) | HTR7 | |
| Hydrochloric Acid SCHEMBL27494195 | 0.83 | KCNQ2 (0.32) | MAPT | |
| Hydrochloric Acid SCHEMBL27493034 | 0.82 | S1PR5 (0.34) | AKR1C3AKR1C2SLC6A4HTR2C | |
| Hydrochloric Acid SCHEMBL27477207 | 0.82 | CYP11B1 (0.35) | MAPTSMN1; SMN2CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL5951958 | 0.81 | NPC1 (0.34) | PPARGPPARANPC1MAPTRAB9A | |
| SCHEMBL27492400 | 0.81 | PPARG (0.31) | PPARGPPARANPC1MAPTRAB9A | |
| Hydrochloric Acid SCHEMBL7185530 | 0.80 | SLC6A4 (0.30) | SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1065241-B1 | Olefinic thermoplastic elastomer composition and method for producing the same | MITSUI CHEMICALS INC (JP) | 2006-04-05 | — | — | EP | disclosed |
| CN-1191286-C | Ethylene copolymer rubber, process for producing same and use | MITSUI CHEMICALS INC (JP) | 2005-03-02 | — | — | CN | disclosed |
| CN-1344283-A | Ethylene copolymer rubber, process for producing the same, and use thereof | MITSUI CHEMICALS INC (JP) | 2002-04-10 | — | — | CN | disclosed |