SCHEMBL2747748

SCHEMBL2747748

C#COC(=O)c1cccc(C(=O)O)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA6 P23280 1/20 0.47
CA9 Q16790 1/20 0.47
AKR1C3 P42330 1/20 0.46
KMO O15229 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C9 P11712 1/20 0.44
HPGD P15428 1/20 0.44
HSD17B10 Q99714 1/20 0.44
UNG P13051 1/20 0.43
FOLH1 Q04609 1/20 0.42
DAO P14920 1/20 0.41
TSHR P16473 1/20 0.41
NAPRT Q6XQN6 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
ATM Q13315 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
TP53 P04637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2747212 0.93 KMO (0.56) CA12CA1CA2CA6CA9
SCHEMBL1712402 0.92 ATM (0.41) CA12CA1CA2CA6CA9
SCHEMBL20183135 0.83 MAPT (0.51) L3MBTL1TDP1PKMKDM4EKMT2A
SCHEMBL28738526 0.82 LOXL2 (0.36) TSHRL3MBTL1ATMTDP1
SCHEMBL1712916 0.82 LMNA (0.56) HSD17B10DAOTSHRNAPRTTDP1
SCHEMBL2746989 0.81 KMO (0.49) KMOTSHRTP53
SCHEMBL2748726 0.80 TSHR (0.52) CA12CA1CA2CA6CA9
SCHEMBL28494891 0.80 PARP1 (0.52) CYP1A2CYP2C9HPGDTDP1KDM4E
SCHEMBL25246556 0.79 DHODH (0.41) CA12CA1CA2CA6CA9
SCHEMBL5689369 0.78 CA12 (0.56) CA12CA1CA2CA6CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8178631-B2 Resin composition, varnish, resin film and semiconductor device SUMITOMO BAKELITE COMPANY, LTD. (JP) 2012-05-15 US disclosed
US-20090214860-A1 Resin Composition, Varnish, Resin Film and Semiconductor Device SUMITOMO BAKELITE COMPANY, LTD. (JP) 2009-08-27 US disclosed
EP-1953181-A1 RESIN COMPOSITION, VARNISH, RESIN FILM AND SEMICONDUCTOR DEVICE Sumitomo Bakelite Company, Ltd. (JP) 2008-08-06 EP disclosed