SCHEMBL2746989

SCHEMBL2746989

C#COC(=O)c1ccc(C(=O)O)cc1.c1cc2cc-2c1

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMO O15229 1/20 0.49
BCL2 P10415 1/20 0.47
RXRA P19793 5/20 0.45
RXRB P28702 5/20 0.45
TRIM24 O15164 1/20 0.45
TRIM33 Q9UPN9 1/20 0.45
EGFR P00533 1/20 0.45
RXRG P48443 1/20 0.44
RARA P10276 1/20 0.42
RARB P10826 1/20 0.42
RARG P13631 1/20 0.42
DHODH Q02127 1/20 0.41
TP53 P04637 1/20 0.40
TSHR P16473 1/20 0.40
EPHX2 P34913 1/20 0.39
NR1H4 Q96RI1 1/20 0.39
LMNA P02545 1/20 0.39
GAA P10253 1/20 0.39
TTR P02766 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2747212 0.89 KMO (0.56) KMOBCL2RXRARXRBDHODH
SCHEMBL2748726 0.88 TSHR (0.52) TP53TSHR
SCHEMBL2747748 0.81 CA12 (0.47) KMOTP53TSHR
SCHEMBL1713017 0.80 ELANE (0.40) TP53TSHRLMNA
SCHEMBL2747742 0.79 ACMSD (0.46) KMODHODHGAA
SCHEMBL1712916 0.78 LMNA (0.56) TP53TSHRLMNA
SCHEMBL1712402 0.76 ATM (0.41) TSHRLMNA
SCHEMBL9426161 0.76 RXRB (0.62) BCL2RXRARXRBEGFRRXRG
SCHEMBL30066684 0.76 KMO (0.72) KMOBCL2RXRARXRBTRIM24
SCHEMBL16166011 0.76 KMO (0.72) KMOBCL2RXRARXRBTRIM24

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8178631-B2 Resin composition, varnish, resin film and semiconductor device SUMITOMO BAKELITE COMPANY, LTD. (JP) 2012-05-15 US disclosed
US-20090214860-A1 Resin Composition, Varnish, Resin Film and Semiconductor Device SUMITOMO BAKELITE COMPANY, LTD. (JP) 2009-08-27 US disclosed
EP-1953181-A1 RESIN COMPOSITION, VARNISH, RESIN FILM AND SEMICONDUCTOR DEVICE Sumitomo Bakelite Company, Ltd. (JP) 2008-08-06 EP disclosed