SCHEMBL2747766

SCHEMBL2747766

CC12CC3(C)CC(c4ccc(O)c(N)c4)(C1)CC(C14CC5(C)CC(C)(CC(c6ccc(O)c(N)c6)(C5)C1)C4)(C2)C3

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.38
HSD17B10 Q99714 5/20 0.38
ALOX15 P16050 4/20 0.38
GAA P10253 9/20 0.35
MEN1 O00255 5/20 0.35
KMT2A Q03164 5/20 0.35
MAPT P10636 5/20 0.35
ALOX12 P18054 3/20 0.35
PKM P14618 3/20 0.35
RECQL P46063 2/20 0.35
HTT P42858 2/20 0.35
HIF1A Q16665 1/20 0.35
HPGD P15428 3/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
MAPK1 P28482 1/20 0.34
KDM4E B2RXH2 3/20 0.34
THRB P10828 2/20 0.34
BLM P54132 1/20 0.34
MCL1 Q07820 1/20 0.34
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2746942 0.77 MMP2 (0.39) ALDH1A1HSD17B10ALOX15GAAMEN1
SCHEMBL3840705 0.76 ESR1 (0.39) ALDH1A1HSD17B10ALOX15MEN1KMT2A
SCHEMBL4583150 0.76 GAA (0.44) ALDH1A1HSD17B10ALOX15GAAMEN1
SCHEMBL5000745 0.76 ALDH1A1 (0.46) ALDH1A1HSD17B10ALOX15GAAMEN1
SCHEMBL2708094 0.75 PTPN11 (0.44) ALDH1A1HSD17B10ALOX15GAAMEN1
SCHEMBL4606957 0.73 ESR1 (0.51) ALDH1A1HSD17B10ALOX15GAAMEN1
SCHEMBL4582985 0.72 ALDH1A1 (0.37) ALDH1A1HSD17B10ALOX15GAAMEN1
SCHEMBL4585323 0.72 ALDH1A1 (0.38) ALDH1A1HSD17B10ALOX15GAAMEN1
SCHEMBL5000706 0.71 MEN1 (0.53) ALDH1A1GAAMEN1KMT2AHTT
SCHEMBL2709672 0.70 PTPN11 (0.39) ALDH1A1GAAMEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8337982-B2 Comprising first repeating unit obtained by reaction of bisaminophenol compound and dicarboxylic acid, at least one of which has diamondoid structure and second repeating unit obtained by reaction of bisaminophenol compound having no diamondoid structure and dicarboxylic acid; heat resistance SUMITOMO BAKELITE CO., LTD. (JP) 2012-12-25 US disclosed
US-8178631-B2 Resin composition, varnish, resin film and semiconductor device SUMITOMO BAKELITE COMPANY, LTD. (JP) 2012-05-15 US disclosed
US-20090214860-A1 Resin Composition, Varnish, Resin Film and Semiconductor Device SUMITOMO BAKELITE COMPANY, LTD. (JP) 2009-08-27 US disclosed
US-20080206548-A1 Benzoxazole Resin Precursor, Polybenzoxazole Resin, Resin Film And Semiconductor Device SUMITOMO BAKELITE CO., LTD (JP) 2008-08-28 US disclosed
EP-1953181-A1 RESIN COMPOSITION, VARNISH, RESIN FILM AND SEMICONDUCTOR DEVICE Sumitomo Bakelite Company, Ltd. (JP) 2008-08-06 EP disclosed
EP-1832619-A1 BENZOXAZOLE RESIN PRECURSOR, POLYBENZOXAZOLE RESIN, RESIN FILM, AND SEMICONDUCTOR DEVICE Sumitomo Bakelite Company, Limited (JP) 2007-09-12 EP disclosed