Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | ICMT | O60725 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ACACA | Q13085 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6246686 | 0.80 | HTR1A (0.47) | MTNR1AMTNR1BCYP1A2CYP2A6 | |
| SCHEMBL6244286 | 0.78 | MTNR1A (0.70) | MTNR1AMTNR1B | |
| SCHEMBL6244266 | 0.74 | MTNR1A (0.53) | MTNR1AMTNR1B | |
| SCHEMBL6249183 | 0.73 | NQO2 (0.53) | MTNR1AMTNR1B | |
| SCHEMBL16371446 | 0.70 | CA2 (0.44) | KDM4ELMNAPOLBMAPK1 | |
| SCHEMBL8575054 | 0.69 | TDP1 (0.60) | MTNR1AMTNR1BKDM4EHPGDMAPT | |
| SCHEMBL3168115 | 0.68 | CYP1A2 (0.67) | BCL2TP53CYP1A2CYP2A6 | |
| SCHEMBL27299050 | 0.68 | KDM4E (0.48) | KDM4EPOLBNPC1ACACACYP1A2 | |
| SCHEMBL1395755 | 0.68 | LMNA (0.69) | KDM4ELMNARAB9ANPC1HPGD | |
| SCHEMBL15963655 | 0.67 | CA2 (0.41) | MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1155562-C | Novel naphthalene compounds, process for their preparation and pharmaceutical compositions containing them | ɪά��ʵ���� | 2004-06-30 | — | — | CN | disclosed |