Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.32 |
| ▸ | ASGR1 | P07306 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24890720 | 0.78 | CNR2 (0.36) | NFKB1NFKB2RELACA14NAMPT | |
| SCHEMBL1962792 | 0.76 | MEN1 (0.45) | NFKB1NFKB2RELACA14L3MBTL1 | |
| SCHEMBL22733859 | 0.75 | CTSD (0.35) | NFKB1NFKB2RELACA14NAMPT | |
| SCHEMBL4780561 | 0.74 | ALOX5 (0.39) | NFKB1NFKB2RELACA14 | |
| SCHEMBL24608436 | 0.74 | ALDH1A1 (0.38) | NFKB1NFKB2RELACA14NAMPT | |
| SCHEMBL22456984 | 0.74 | CCR2 (0.41) | NFKB1NFKB2RELAL3MBTL1 | |
| SCHEMBL17686995 | 0.73 | CA14 (0.39) | NFKB1NFKB2RELACA14NAMPT | |
| SCHEMBL4669068 | 0.72 | CTSD (0.35) | NFKB1NFKB2RELACA14KMT2A | |
| SCHEMBL7505005 | 0.72 | CHRM1 (0.35) | NFKB1NFKB2RELACA14L3MBTL1 | |
| SCHEMBL15725091 | 0.71 | CA14 (0.40) | NFKB1NFKB2RELACA14NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145483-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF CANCER AND METHODS OF MAKING AND USING THE SAME | HTG MOLECULAR DIAGNOSTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |