Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | LIG1 | P18858 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27479938 | 0.87 | HPGD (0.31) | KDM4EPKMLIG1HPGDALDH1A1 | |
| SCHEMBL27576498 | 0.77 | CXCR2 (0.42) | ALDH1A1 | |
| SCHEMBL6818586 | 0.72 | CXCR2 (0.46) | PKMLIG1ALDH1A1 | |
| SCHEMBL6818590 | 0.72 | CXCR2 (0.44) | KDM4ELIG1ALDH1A1 | |
| SCHEMBL506595 | 0.70 | ALDH1A1 (0.42) | KDM4EPKMLIG1HPGDALDH1A1 | |
| SCHEMBL6818541 | 0.68 | HPGD (0.33) | KDM4ELIG1HPGDALDH1A1CA12 | |
| SCHEMBL6550839 | 0.67 | TRPV4 (0.38) | KDM4EHPGDALDH1A1CA12CA1 | |
| SCHEMBL6818508 | 0.66 | CXCR2 (0.44) | KDM4ELIG1HPGDALDH1A1TSHR | |
| SCHEMBL6818505 | 0.66 | CXCR2 (0.44) | KDM4ELIG1HPGDALDH1A1TSHR | |
| SCHEMBL21728097 | 0.66 | AR (0.44) | KDM4EHPGDALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1152675-C | IL-8 receptor antagonists | ʷ��˿�������ȳ�ķ����˾ | 2004-06-09 | — | — | CN | disclosed |
| CN-1232398-A | IL-8 receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 1999-10-20 | — | — | CN | disclosed |