Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.54 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2425338 | 0.85 | MAPK9 (0.72) | MAPK9MAPK10USP2MAPTKDM4E | |
| SCHEMBL27494742 | 0.79 | MAPK9 (0.57) | MAPK9MAPK10USP2MAPTKDM4E | |
| SCHEMBL27494743 | 0.78 | MAPK9 (0.63) | MAPK9MAPK10USP2MAPTMEN1 | |
| SCHEMBL27479119 | 0.78 | MAPK9 (0.63) | MAPK9MAPK10USP2MEN1KMT2A | |
| SCHEMBL27477824 | 0.73 | MAPK9 (0.40) | MAPK9MAPK10USP2MAPTKDM4E | |
| SCHEMBL4189472 | 0.72 | MAPK9 (0.72) | MAPK9MAPK10USP2MAPTALDH1A1 | |
| SCHEMBL1518774 | 0.70 | MAPK9 (1.00) | MAPK9MAPK10USP2ALDH1A1MEN1 | |
| SCHEMBL2422059 | 0.68 | OPRM1 (0.50) | MAPK9MAPK10USP2MAPTALDH1A1 | |
| SCHEMBL27495526 | 0.67 | MAPK9 (0.49) | MAPK9MAPK10MAPTKDM4EMEN1 | |
| SCHEMBL4413374 | 0.67 | MAPK9 (0.76) | MAPK9MAPK10USP2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1189467-C | Pharmaceutically active sulfonamide derivatives | APPLIED RES SYSTEM ARS HOLDING (AN) | 2005-02-16 | — | — | CN | disclosed |
| CN-1377347-A | Pharmaceutically active sulfonamide derivatives | APPLIED RESEARCH SYSTEMS (NL) | 2002-10-30 | — | — | CN | disclosed |