SCHEMBL2747980

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2747131	0.91	KDR (0.74)	EGFRMAPK14KDR
	SCHEMBL2747187	0.88	KDR (0.71)	EGFRMAPK14KDR
	SCHEMBL2746962	0.84	KDR (0.62)	EGFRMAPK14SRCKDRLCK
	SCHEMBL2746015	0.84	KDR (0.62)	EGFRMAPK14SRCKDRLCK
	SCHEMBL31067722	0.83	EGFR (0.84)	EGFRKDM4EMAPTMAPK1MAPK14
	Tyrphostin Ag-1478 SCHEMBL31079458	0.83	EGFR (1.00)	EGFRKDM4EMAPTMAPK1MAPK14
	Tyrphostin Ag-1478 SCHEMBL29483198	0.83	EGFR (1.00)	EGFRKDM4EMAPTMAPK1MAPK14
	Tyrphostin Ag-1478 SCHEMBL93838	0.83	EGFR (1.00)	EGFRKDM4EMAPTMAPK1MAPK14
	Tyrphostin Ag-1478 SCHEMBL29350062	0.83	EGFR (1.00)	EGFRKDM4EMAPTMAPK1MAPK14
	SCHEMBL4549037	0.82	KDR (0.69)	EGFRMAPK14ABL1KDRLCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.