Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRB | O95718 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL28008035 | 0.98 | ESRRB (0.47) | ESRRBPOLBALDH1A1KDM4ELMNA | |
| Biphenyl SCHEMBL3991647 | 0.86 | POLB (0.47) | POLBALDH1A1KDM4ELMNAGLA | |
| Catechol SCHEMBL27778055 | 0.86 | LMNA (0.48) | ESRRBPOLBALDH1A1KDM4ELMNA | |
| Phenol SCHEMBL11702329 | 0.84 | MGAM (0.60) | ESRRBPOLBALDH1A1KDM4ELMNA | |
| Toluene SCHEMBL27945492 | 0.84 | POLB (0.46) | POLBALDH1A1KDM4ELMNATDP1 | |
| Benzene SCHEMBL28161453 | 0.83 | LMNA (0.54) | POLBALDH1A1KDM4ELMNAGAA | |
| Chlorobenzene SCHEMBL27773693 | 0.82 | POLB (0.44) | POLBALDH1A1KDM4ELMNATSHR | |
| Benzophenone SCHEMBL7081803 | 0.82 | ALDH1A1 (0.54) | POLBALDH1A1LMNATDP1TSHR | |
| Bromobenzene SCHEMBL28295090 | 0.82 | HPGD (0.45) | POLBALDH1A1KDM4ELMNATDP1 | |
| Anisole SCHEMBL28296887 | 0.82 | CA4 (0.54) | POLBALDH1A1CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109867687-A | A kind of highly-water-soluble Amoxicillin and preparation method thereof | 上海朝瑞化工有限公司 | 2019-06-11 | — | — | CN | claimed |
| CN-105368910-B | A kind of method of enzymatic clarification Cefprozil | 苏州中联化学制药有限公司 | 2019-01-11 | — | — | CN | claimed |
| CN-107988306-A | A kind of half method through synthesis Amoxicillin and the method for by-product sodium phenylacetate solution | 内蒙古常盛制药有限公司 | 2018-05-04 | — | — | CN | claimed |
| CN-104357528-B | The method of active ingredient in synthetical recovery enzymatic amoxicillin mother liquor | 国药集团威奇达药业有限公司 | 2018-04-27 | — | — | CN | claimed |
| CN-107937472-A | A kind of method of straight-through synthesis Amoxicillin | 内蒙古常盛制药有限公司 | 2018-04-20 | — | — | CN | claimed |
| CN-107881209-A | The method of enzymatic clarification Cefprozil | 福安药业集团重庆博圣制药有限公司 | 2018-04-06 | — | — | CN | claimed |
| CN-107058447-A | A kind of method of enzymatic clarification cefadroxil | 苏州中联化学制药有限公司 | 2017-08-18 | — | — | CN | claimed |
| CN-105254520-B | The recovery method of D D-pHPGs in the crystalline mother solution of enzymatic clarification Amoxicillin | 国药集团威奇达药业有限公司 | 2017-07-07 | — | — | CN | claimed |
| CN-106497989-A | A kind of method that amoxicillin and phenylacetic acid are prepared by benzylpenicillin potassium | 内蒙古常盛制药有限公司 | 2017-03-15 | — | — | CN | claimed |
| CN-106399446-A | Method for preparing amoxicillin from degreased liquid | 内蒙古常盛制药有限公司 | 2017-02-15 | — | — | CN | claimed |
| CN-105368910-A | Method for synthesizing cefprozil through enzymatic method | CHINA UNION CHEMPHARMA (SUZHOU) CO LTD | 2016-03-02 | — | — | CN | claimed |
| CN-105254520-A | Recovery method for D-hydroxyphenylglycine in amoxicillin crystallization mother liquor of enzymatic synthesis | WEIQIDA PHARMACEUTICAL CO LTD OF CHINA NAT PHARMACEUTICAL INDUSTRY CORP LTD | 2016-01-20 | — | — | CN | claimed |
| CN-104928340-A | Process for enzymatic synthesis of cefprozil | SHANDONG LUKANG RECORD PHARMACEUTICALS CO LTD | 2015-09-23 | — | — | CN | claimed |
| CN-104892444-A | Method for synthesizing D-p-hydroxyphenylglycine methyl ester | SHANXI XINGHUO WEIMIN PHARMACEUTICAL CO LTD | 2015-09-09 | — | — | CN | claimed |
| CN-104830940-A | An enzymatic synthesis process of Amoxicillin | SHANDONG LUKANG RECORD PHARMACEUTICALS CO LTD | 2015-08-12 | — | — | CN | claimed |
| CN-104744281-A | Synthetic method of D-p-hydroxyphenylglycine methyl ester | HENAN NEWLAND PHARM CO LTD | 2015-07-01 | — | — | CN | claimed |
| CN-103641729-B | Preparation method of methyl D-4-hydroxy-phenylglycinate and hydrochloride thereof | HEBEI IFORT FINE CHEMICAL CO LTD | 2015-04-08 | — | — | CN | claimed |
| CN-104357528-A | Method for comprehensively recovering effective ingredients in amoxicillin mother liquid prepared by enzyme process | SINOPHARM WEIQIDA PHARMACEUTICAL CO LTD | 2015-02-18 | — | — | CN | claimed |
| CN-110520432-A | Optically active 2-amino-phosphonoalkanoic acid, optically active 2-amino-phosphonoalkanoic acid salt and hydrate thereof | NAHLS CORP CO LTD | 2019-11-29 | — | — | CN | disclosed |
| CN-85101892-B | Process for preparing novel 1, 5-benzothiazepine derivatives | 田边制药株式会社 | 1988-03-02 | — | — | CN | disclosed |