Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | ELANE | P08246 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.46 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7546053 | 0.85 | TSHR (0.47) | ALDH1A1TSHRTDP1AKT1HPGD | |
| Biphenyl SCHEMBL3991647 | 0.84 | POLB (0.47) | ALDH1A1TSHRL3MBTL1HPGDRAB9A | |
| Phenol SCHEMBL27480309 | 0.82 | ESRRB (0.49) | ALDH1A1TSHRTDP1AKT1HPGD | |
| Toluene SCHEMBL27945492 | 0.82 | POLB (0.46) | ALDH1A1TSHRL3MBTL1TDP1AKT1 | |
| Benzophenone SCHEMBL28209504 | 0.81 | ELANE (0.51) | ALDH1A1ELANETSHRL3MBTL1HPGD | |
| Hydrochloric Acid SCHEMBL26119947 | 0.81 | TSHR (0.52) | ALDH1A1TSHRL3MBTL1TDP1AKT1 | |
| Benzene SCHEMBL28161453 | 0.81 | LMNA (0.54) | ALDH1A1TSHRAKT1LMNAPOLB | |
| Chlorobenzene SCHEMBL27773693 | 0.81 | POLB (0.44) | ALDH1A1TSHRAKT1RAB9APTGS2 | |
| Anisole SCHEMBL28296887 | 0.81 | CA4 (0.54) | ALDH1A1L3MBTL1TDP1RAB9APOLB | |
| Phenol SCHEMBL28008035 | 0.81 | ESRRB (0.47) | ALDH1A1TSHRTDP1AKT1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030162778-A1 | Carbocyclic side chain containing metalloprotease inhibitors | THE PROCTER AND GAMBLE COMPANY | 2003-08-28 | — | — | US | disclosed |
| US-20030144292-A1 | Carbocyclic side chain containing, N-substituted metalloprotease inhibitors | PROCTER & GAMBLE COMPANY, THE | 2003-07-31 | — | — | US | disclosed |
| CN-1418209-A | Carbocyclic side chain containing metalloprotease inhibitors | PROCTER & GAMBLE (US) | 2003-05-14 | — | — | CN | disclosed |
| CN-1418210-A | Carbocyclik side chain containing, N-substituted Metalloprotease inhibitors | PROCTER & GAMBLE (US) | 2003-05-14 | — | — | CN | disclosed |
| EP-1265886-A2 | CARBOCYCLIC SIDE CHAIN CONTAINING, N-SUBSTITUTED METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2002-12-18 | — | — | EP | disclosed |
| EP-1265887-A2 | CARBOCYCLIC SIDE CHAIN CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2002-12-18 | — | — | EP | disclosed |
| WO-2001070682-A2 | CARBOCYCLIC SIDE CHAIN CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2001-09-27 | — | — | WO | disclosed |
| WO-2001070720-A2 | CARBOCYCLIC SIDE CHAIN CONTAINING, N-SUBSTITUTED METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2001-09-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162778-A1 | Carbocyclic side chain containing metalloprotease inhibitors | MMP2, CMA1, SERPINB1 | ALDH1A1 413/4885ELANE 59/4885TSHR 3827/4885 |
| US-20030144292-A1 | Carbocyclic side chain containing, N-substituted metalloprotease inhibitors | MMP2, MMP3, CMA1 | ALDH1A1 494/4885ELANE 42/4885TSHR 3816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.