Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.42 |
| ▸ | CEL | P19835 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | EBP | Q15125 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3786167 | 0.85 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| SCHEMBL8331330 | 0.83 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| SCHEMBL3785820 | 0.83 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| SCHEMBL3784884 | 0.79 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| SCHEMBL3786279 | 0.75 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| SCHEMBL434608 | 0.72 | GAA (0.56) | CELSIGMAR1TMEM97EBPGAA | |
| SCHEMBL3787199 | 0.71 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| SCHEMBL9751699 | 0.70 | HTR2A (0.37) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| SCHEMBL432639 | 0.70 | GAA (0.58) | CELGAATSHRAGTR1 | |
| SCHEMBL4331978 | 0.70 | SLC6A2 (0.68) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1226825-A | Use of amines to produce drugs for preventing tumour cell proliferation | SANOFI SA (FR) | 1999-08-25 | — | — | CN | claimed |
| CN-1154483-C | Use of amines to produce drugs for preventing tumour cell proliferation | ��ŵ��-ʥ�������ɷ�����˾ | 2004-06-23 | — | — | CN | disclosed |
| CN-1226825-A | Use of amines to produce drugs for preventing tumour cell proliferation | SANOFI SA (FR) | 1999-08-25 | — | — | CN | disclosed |