Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30623705 | 0.85 | NPC1 (0.47) | TSHRNPC1L3MBTL1LMNAHPGD | |
| SCHEMBL3806746 | 0.85 | NPC1 (0.47) | TSHRNPC1L3MBTL1LMNAHPGD | |
| SCHEMBL9786704 | 0.83 | ALDH1A1 (0.52) | TSHRALDH1A1ALOX15CYP3A4NPC1 | |
| SCHEMBL9895330 | 0.82 | MAPT (0.34) | TSHRALDH1A1ALOX15CES2CES1 | |
| SCHEMBL28035137 | 0.82 | NR4A1 (0.55) | ALDH1A1CYP3A4NPC1L3MBTL1LMNA | |
| SCHEMBL9895706 | 0.81 | ALDH1A1 (0.32) | TSHRALDH1A1ALOX15CES2CES1 | |
| Bicarbonate SCHEMBL27331839 | 0.80 | NPC1 (0.47) | TSHRNPC1L3MBTL1LMNAHPGD | |
| SCHEMBL8028505 | 0.79 | TSHR (0.78) | TSHRALDH1A1CYP3A4TDP1L3MBTL1 | |
| SCHEMBL1151641 | 0.78 | LMNA (0.58) | TSHRALDH1A1CES2CES1TDP1 | |
| SCHEMBL5806487 | 0.77 | ALDH1A1 (0.50) | TSHRALDH1A1ALOX15CYP3A4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1504460-A | Bulk dyeing using quinophthalone dyestuffs | — | 2004-06-16 | — | — | CN | claimed |
| CN-1197083-A | Bulk dyeing process using quinolone derivative dyes | BAYER AG (DE) | 1998-10-28 | — | — | CN | claimed |
| CN-1504460-A | Bulk dyeing using quinophthalone dyestuffs | — | 2004-06-16 | — | — | CN | disclosed |
| CN-1197083-A | Bulk dyeing process using quinolone derivative dyes | BAYER AG (DE) | 1998-10-28 | — | — | CN | disclosed |