Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27502325 | 0.86 | MEN1 (0.35) | ALDH1A1LMNABLM | |
| SCHEMBL27503047 | 0.85 | CRHBP (0.35) | HDAC4LMNABLMHDAC3HDAC1 | |
| SCHEMBL27561719 | 0.82 | CDC25B (0.32) | LMNA | |
| SCHEMBL27484414 | 0.82 | HCAR2 (0.33) | HDAC4HCAR2HDAC3HDAC1HDAC2 | |
| SCHEMBL27484786 | 0.81 | KDM4E (0.38) | — | |
| SCHEMBL27529127 | 0.81 | SLC6A2 (0.30) | — | |
| SCHEMBL27486165 | 0.81 | MAPT (0.42) | ALDH1A1GAALMNA | |
| SCHEMBL27504464 | 0.79 | HSD11B1 (0.35) | ALDH1A1GAALMNA | |
| SCHEMBL27486162 | 0.75 | CCR2 (0.34) | ALDH1A1GAALMNA | |
| SCHEMBL27504121 | 0.74 | HSD11B1 (0.33) | ALDH1A1HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1196721-A | Heteroaryl-substituted acryloylguanidine derivatives and medicinal composition thereof | YAMANOUCHI PHARMA CO LTD (JP) | 1998-10-21 | — | — | CN | disclosed |