Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNPAT | O15228 | 2/20 | 0.40 |
| ▸ | ALB | P02768 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LONP1 | P36776 | 3/20 | 0.36 |
| ▸ | GPR132 | Q9UNW8 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6190867 | 0.83 | NLRP3 (0.42) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL6190862 | 0.83 | NLRP3 (0.42) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL6801056 | 0.76 | ALB (0.53) | GNPATALBKDM4EMAPTTHRB | |
| SCHEMBL24016465 | 0.74 | KDM4E (0.46) | KDM4EKMT2A | |
| SCHEMBL27485143 | 0.73 | ALB (0.42) | GNPATALBKDM4EMAPTTHRB | |
| SCHEMBL8766796 | 0.72 | KDM4E (0.34) | KDM4EMAPTLONP1PSMB5LMNA | |
| SCHEMBL18110415 | 0.72 | LMNA (0.35) | KDM4ESMN1; SMN2ALDH1A1LONP1GPR132 | |
| SCHEMBL16745724 | 0.72 | GNPAT (0.62) | GNPATALBKDM4EMAPTTHRB | |
| SCHEMBL15798754 | 0.71 | ALDH1A1 (0.36) | KDM4ESMN1; SMN2ALDH1A1LONP1PSMB5 | |
| SCHEMBL14400980 | 0.71 | GNPAT (0.61) | GNPATALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1202096-C | 2-aminothiazoline derivatives and their use as no-synthase inhibitors | AVENTIS PHARMA SA (FR) | 2005-05-18 | — | — | CN | disclosed |
| CN-1444572-A | 2-aminothiazoline derivatives and their use as no-synthase inhibitors | AVENTIS PHARMA SA (FR) | 2003-09-24 | — | — | CN | disclosed |