Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.40 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27521095 | 0.91 | KMT2A (0.42) | GPR139KMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL27501985 | 0.88 | ITGB1 (0.44) | GPR139KMT2AMEN1SMN1; SMN2ITGB1 | |
| SCHEMBL27503083 | 0.87 | HTT (0.43) | GPR139KMT2ASMN1; SMN2ALDH1A1ITGB1 | |
| SCHEMBL27484818 | 0.86 | SMN1; SMN2 (0.40) | GPR139KMT2ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL7343510 | 0.84 | GPR139 (0.51) | GPR139KMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL27486185 | 0.83 | ALDH1A1 (0.41) | GPR139KMT2AMEN1ALDH1A1ITGB1 | |
| SCHEMBL27486186 | 0.83 | ITGB1 (0.39) | GPR139KMT2AMEN1SMN1; SMN2ITGB1 | |
| SCHEMBL6778010 | 0.83 | GPR139 (0.49) | GPR139KMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL27504167 | 0.81 | ITGB1 (0.51) | GPR139SMN1; SMN2ITGB1ITGA5HTT | |
| SCHEMBL27485520 | 0.80 | HTT (0.42) | GPR139KMT2AMEN1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1201454-A | Meta-guanidino, ureido, thioureido or azacyclic aminobenzoic acid derivatives as integrin antagonists | SEARLE & CO (US) | 1998-12-09 | — | — | CN | claimed |