Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27555299 | 0.89 | POLB (0.55) | LMNAALDH1A1HDAC1HDAC2HDAC6 | |
| SCHEMBL8390400 | 0.87 | ADORA1 (0.54) | LMNAALDH1A1HDAC1HDAC2HDAC6 | |
| SCHEMBL27522647 | 0.81 | MAPT (0.52) | LMNAALDH1A1MAPTHPGDTSHR | |
| SCHEMBL8802855 | 0.80 | LMNA (0.64) | LMNAALDH1A1HDAC1HDAC2HDAC6 | |
| SCHEMBL27486760 | 0.79 | LMNA (0.61) | LMNAALDH1A1HDAC1HDAC2HDAC6 | |
| SCHEMBL8388127 | 0.76 | POLB (0.60) | ALDH1A1HPGDADORA1SERPINE1POLB | |
| SCHEMBL2438014 | 0.75 | ITGB1 (0.51) | HDAC1HDAC6MAPTHPGDTSHR | |
| SCHEMBL27475773 | 0.74 | HDAC8 (0.62) | HDAC1HDAC2HDAC6MAPTHPGD | |
| SCHEMBL1562983 | 0.73 | HDAC1 (0.77) | LMNAALDH1A1HDAC1HDAC2HDAC6 | |
| SCHEMBL11470606 | 0.73 | SRD5A2 (0.50) | LMNAALDH1A1MAPTHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1166169-A | Heterocyclic compounds, useful as allosteric effectors at muscarinic receptors | SANKYO CO (JP) | 1997-11-26 | — | — | CN | disclosed |