Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | SLC22A12 | Q96S37 | 8/20 | 0.58 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27555299 | 0.88 | POLB (0.55) | POLBSLC22A12SERPINE1L3MBTL1ALDH1A1 | |
| SCHEMBL8390400 | 0.86 | ADORA1 (0.54) | SLC22A12SERPINE1KDM4EALDH1A1ADORA1 | |
| SCHEMBL8602152 | 0.84 | SLC22A12 (0.78) | SLC22A12KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL11976676 | 0.83 | SLC22A12 (0.73) | POLBSLC22A12SERPINE1KDM4EALDH1A1 | |
| SCHEMBL30049353 | 0.82 | POLB (0.79) | POLBL3MBTL1KDM4EALDH1A1MAPK1 | |
| SCHEMBL17324721 | 0.82 | POLB (0.79) | POLBL3MBTL1KDM4EALDH1A1MAPK1 | |
| SCHEMBL9056108 | 0.80 | LMNA (0.55) | POLBSERPINE1L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL8389104 | 0.80 | ALDH1A1 (0.55) | SLC22A12SERPINE1KDM4EALDH1A1HPGD | |
| SCHEMBL16259052 | 0.79 | POLB (0.53) | POLBSERPINE1L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL27555301 | 0.77 | L3MBTL1 (0.53) | POLBSERPINE1L3MBTL1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5877199-A | ALZHEIMER'S DISEASE; SEDATIVE | SANKYO COMPANY, LIMITED (JP) | 1999-03-02 | — | — | US | disclosed |
| WO-1996003377-A1 | HETEROCYCLIC COMPOUNDS, USEFUL AS ALLOSTERIC EFFECTORS AT MUSCARINIC RECEPTORS | SANKYO COMPANY, LIMITED (JP) | 1996-02-08 | — | — | WO | disclosed |