Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | SNCA | P37840 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8389104 | 0.87 | ALDH1A1 (0.55) | MAPTHPGDALDH1A1SMN1; SMN2HTT | |
| SCHEMBL27555299 | 0.83 | POLB (0.55) | MAPTHPGDTSHRALDH1A1HTT | |
| SCHEMBL27486759 | 0.81 | LMNA (0.56) | MAPTHPGDTSHRALDH1A1HTT | |
| SCHEMBL2161419 | 0.78 | CNR2 (0.56) | MAPTALDH1A1SMN1; SMN2HTTAPP | |
| SCHEMBL8801519 | 0.78 | ALDH1A1 (0.48) | MAPTHPGDALDH1A1SMN1; SMN2HTT | |
| SCHEMBL17829679 | 0.76 | ALDH1A1 (0.57) | MAPTALDH1A1SMN1; SMN2HTTSNCA | |
| SCHEMBL3145711 | 0.76 | ALDH1A1 (0.64) | MAPTALDH1A1SMN1; SMN2HTTAPP | |
| SCHEMBL9732936 | 0.76 | MAPT (0.54) | MAPTHPGDALDH1A1SMN1; SMN2HTT | |
| SCHEMBL1082596 | 0.75 | ALDH1A1 (0.56) | MAPTALDH1A1SMN1; SMN2HTTSNCA | |
| SCHEMBL1607759 | 0.75 | HDAC6 (0.54) | ALDH1A1SMN1; SMN2CNR2LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1166169-A | Heterocyclic compounds, useful as allosteric effectors at muscarinic receptors | SANKYO CO (JP) | 1997-11-26 | — | — | CN | disclosed |