Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | TP53 | P04637 | 4/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9056108 | 0.91 | LMNA (0.55) | LMNAALDH1A1HDAC1HDAC2HDAC6 | |
| SCHEMBL27486760 | 0.90 | LMNA (0.61) | LMNAALDH1A1HDAC1HDAC2HDAC6 | |
| SCHEMBL1562983 | 0.81 | HDAC1 (0.77) | LMNAALDH1A1HDAC1HDAC2HDAC6 | |
| SCHEMBL8801519 | 0.81 | ALDH1A1 (0.48) | LMNAALDH1A1MAPT | |
| SCHEMBL27555301 | 0.81 | L3MBTL1 (0.53) | LMNAALDH1A1HDAC1HDAC2HDAC6 | |
| SCHEMBL8390400 | 0.80 | ADORA1 (0.54) | LMNAALDH1A1HDAC1HDAC2HDAC6 | |
| SCHEMBL27486759 | 0.80 | LMNA (0.56) | LMNAALDH1A1HDAC1HDAC2HDAC6 | |
| SCHEMBL10095262 | 0.77 | LMNA (0.58) | LMNAALDH1A1HDAC1HDAC2HDAC6 | |
| SCHEMBL15712247 | 0.76 | LMNA (0.60) | LMNAALDH1A1MAPTTP53MAPK1 | |
| SCHEMBL1548669 | 0.75 | LMNA (0.94) | LMNAALDH1A1MAPTTP53RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1166169-A | Heterocyclic compounds, useful as allosteric effectors at muscarinic receptors | SANKYO CO (JP) | 1997-11-26 | — | — | CN | disclosed |
| EP-0804416-A1 | HETEROCYCLIC COMPOUNDS, USEFUL AS ALLOSTERIC EFFECTORS AT MUSCARINIC RECEPTORS | SANKYO COMPANY LIMITED (JP) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996003377-A1 | HETEROCYCLIC COMPOUNDS, USEFUL AS ALLOSTERIC EFFECTORS AT MUSCARINIC RECEPTORS | SANKYO COMPANY, LIMITED (JP) | 1996-02-08 | — | — | WO | disclosed |