Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 17/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 13/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27469593 | 0.86 | PTGS2 (0.55) | PTGS2PTGS1ITGB1ITGA4ITGB7 | |
| SCHEMBL27489272 | 0.86 | PTGS2 (0.39) | PTGS2PTGS1 | |
| SCHEMBL27486819 | 0.83 | PTGS2 (0.38) | PTGS2PTGS1ITGB1ITGA4ITGB7 | |
| SCHEMBL27486815 | 0.81 | PTGS2 (0.44) | PTGS2PTGS1ITGB1ITGA4ITGB7 | |
| SCHEMBL27487526 | 0.80 | CYP1A2 (0.47) | PTGS2PTGS1ITGB1ITGA4ITGB7 | |
| SCHEMBL27488603 | 0.80 | PTGS2 (0.42) | PTGS2PTGS1ITGB1ITGA4ITGB7 | |
| SCHEMBL27489264 | 0.80 | PTGS2 (0.42) | PTGS2PTGS1 | |
| SCHEMBL27469590 | 0.80 | PTGS2 (0.58) | PTGS2PTGS1 | |
| SCHEMBL4189991 | 0.80 | PTGS2 (0.65) | PTGS2PTGS1 | |
| SCHEMBL27489270 | 0.80 | PTGS2 (0.42) | PTGS2PTGS1ITGB1ITGA4ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1167687-C | Arylpyridazinones as prostaglandin endoperoxide H synthase biosynthesis inhibitors | ���Ͽع�����˾ | 2004-09-22 | — | — | CN | disclosed |