Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 13/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 10/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | USP7 | Q93009 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27489270 | 0.89 | PTGS2 (0.42) | PTGS2ALDH1A1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL27487893 | 0.89 | CYP1A2 (0.47) | PTGS2SMN1; SMN2RAB9APTGS1HTT | |
| SCHEMBL27487526 | 0.89 | CYP1A2 (0.47) | PTGS2SMN1; SMN2RAB9APTGS1HTT | |
| SCHEMBL27488603 | 0.89 | PTGS2 (0.42) | PTGS2ALDH1A1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL27469593 | 0.89 | PTGS2 (0.55) | PTGS2ALDH1A1L3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL27475808 | 0.87 | PTGS2 (0.42) | PTGS2ALDH1A1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL27489265 | 0.86 | PGR (0.46) | PTGS2ALDH1A1L3MBTL1SMN1; SMN2PTGS1 | |
| SCHEMBL27489268 | 0.86 | PTGS2 (0.43) | PTGS2ALDH1A1L3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL27487525 | 0.85 | SRC (0.46) | PTGS2ALDH1A1RAB9ALMNANPC1 | |
| SCHEMBL27549345 | 0.85 | PTGS2 (0.43) | PTGS2ALDH1A1SMN1; SMN2RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1167687-C | Arylpyridazinones as prostaglandin endoperoxide H synthase biosynthesis inhibitors | ���Ͽع�����˾ | 2004-09-22 | — | — | CN | disclosed |