Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 12/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 9/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27487893 | 1.00 | CYP1A2 (0.47) | CYP1A2PTGS2PTGS1SMN1; SMN2HTT | |
| SCHEMBL27549346 | 0.91 | PTGS2 (0.41) | CYP1A2PTGS2PTGS1ITGB1ITGA4 | |
| SCHEMBL27488603 | 0.89 | PTGS2 (0.42) | CYP1A2PTGS2PTGS1SMN1; SMN2HTT | |
| SCHEMBL27489264 | 0.89 | PTGS2 (0.42) | PTGS2PTGS1SMN1; SMN2HTTRAB9A | |
| SCHEMBL27489270 | 0.89 | PTGS2 (0.42) | CYP1A2PTGS2PTGS1SMN1; SMN2HTT | |
| SCHEMBL27469593 | 0.89 | PTGS2 (0.55) | PTGS2PTGS1SMN1; SMN2ITGB1ITGA4 | |
| SCHEMBL27549345 | 0.87 | PTGS2 (0.43) | CYP1A2PTGS2PTGS1SMN1; SMN2HTT | |
| SCHEMBL27489265 | 0.86 | PGR (0.46) | PTGS2PTGS1SMN1; SMN2HTTITGB1 | |
| SCHEMBL27489268 | 0.86 | PTGS2 (0.43) | PTGS2PTGS1SMN1; SMN2RAB9A | |
| SCHEMBL27486815 | 0.86 | PTGS2 (0.44) | PTGS2PTGS1SMN1; SMN2HTTITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1167687-C | Arylpyridazinones as prostaglandin endoperoxide H synthase biosynthesis inhibitors | ���Ͽع�����˾ | 2004-09-22 | — | — | CN | disclosed |