SCHEMBL27487512

SCHEMBL27487512

Oc1ccccc1-c1cccc2cc[nH]c12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 2/20 0.47
KEAP1 Q14145 1/20 0.46
PDPK1 O15530 1/20 0.44
NR3C1 P04150 6/20 0.40
REN P00797 2/20 0.40
GUSB P08236 1/20 0.39
BACE1 P56817 1/20 0.39
IDO1 P14902 1/20 0.39
CYP1A2 P05177 1/20 0.39
ALDH1A1 P00352 1/20 0.39
HPGD P15428 1/20 0.39
BCL2L1 Q07817 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TRPA1 O75762 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
ITGB2 P05107 1/20 0.39
ICAM1 P05362 1/20 0.39
ITGAL P20701 1/20 0.39
CA4 P22748 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31492457 0.85 AHR (0.60) AHRKEAP1PDPK1NR3C1REN
SCHEMBL109665 0.81 AHR (0.56) AHRKEAP1PDPK1NR3C1BACE1
SCHEMBL29617963 0.81 AHR (0.56) AHRKEAP1PDPK1NR3C1BACE1
SCHEMBL16719976 0.80 AHR (0.40) AHRKEAP1PDPK1NR3C1REN
SCHEMBL29876050 0.79 AHR (0.54) AHRKEAP1PDPK1NR3C1BACE1
Hydrochloric Acid SCHEMBL28190395 0.79 AHR (0.54) AHRKEAP1PDPK1NR3C1BACE1
SCHEMBL4173132 0.78 REN (0.49) AHRKEAP1NR3C1RENPGR
SCHEMBL7089560 0.77 AHR (0.68) AHRKEAP1PDPK1NR3C1REN
SCHEMBL5659490 0.77 AHR (0.47) AHRKEAP1PDPK1NR3C1REN
SCHEMBL16719974 0.76 AHR (0.40) AHRKEAP1PDPK1NR3C1REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1937994-A Keratin dyeing compounds, keratin dyeing compositions containing them and their use PROCTER & GAMBLE (US) 2007-03-28 CN disclosed
CN-1937995-A Keratin dyeing compositions comprising bicyclic 5-6 heteroaromatic dyeing compounds containing a ring-connected nitrogen atom PROCTER & GAMBLE (US) 2007-03-28 CN disclosed
CN-1264498-C Primary intermediates for oxidative dyeing of hair PROCTER & GAMBLE (US) 2006-07-19 CN disclosed
CN-1239467-C Primary intermediates for oxidative dyeing of hair P & G CLAIROL INC (US) 2006-02-01 CN disclosed
CN-1229102-C Novel couplers for oxidative hair dyeing P & G CLAIROL INC (US) 2005-11-30 CN disclosed
CN-1229100-C Primary intermediates for oxidative dyeing of hair P & G CLAIROL INC (US) 2005-11-30 CN disclosed
CN-1224374-C Novel couplers for oxidative hair dyeing P & G CLAIROL INC (US) 2005-10-26 CN disclosed
CN-1219501-C Primary intermediates for oxidative dyeing of hair P & G CLAIROL INCORP (US) 2005-09-21 CN disclosed
CN-1213722-C Couplers for oxidative hair dyeing P & G CLAIROL INC (US) 2005-08-10 CN disclosed
CN-1198574-C Novel couplers for oxidative hair dyeing P & G CLAIROL INC (US) 2005-04-27 CN disclosed
CN-1486297-A Primary intermediates for oxidative dyeing of hair P&G 2004-03-31 CN disclosed
CN-1486170-A Novel couplers for use in oxidative hair dyeing P&G 2004-03-31 CN disclosed
CN-1486172-A Primary intermediates for oxidative dyeing of hair P&G 2004-03-31 CN disclosed
CN-1486171-A Couplers for oxidative hair dyeing P&G克莱罗尔公司 2004-03-31 CN disclosed
CN-1477948-A Novel couplers for oxidative hair dyeing P&G克莱罗尔公司 2004-02-25 CN disclosed
CN-1477947-A Primary intermediates for oxidative dyeing of hair P&G 2004-02-25 CN disclosed
CN-1474681-A Novel couplers for oxidative hair dyeing P&G克莱罗尔公司 2004-02-11 CN disclosed
CN-1474680-A Novel couplers for oxidative hair dyeing P&G克莱罗尔公司 2004-02-11 CN disclosed
CN-1474679-A Novel couplers for oxidative hair dyeing P&G 2004-02-11 CN disclosed
CN-1449276-A Primary intermediates for oxidative dyeing of hair P & G CLAIROL INC (US) 2003-10-15 CN disclosed