Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 13/20 | 0.36 |
| ▸ | REN | P00797 | 2/20 | 0.35 |
| ▸ | PGR | P06401 | 5/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.34 |
| ▸ | AR | P10275 | 3/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27487512 | 0.80 | AHR (0.47) | AHRKEAP1PDPK1NR3C1REN | |
| SCHEMBL31492457 | 0.77 | AHR (0.60) | AHRKEAP1PDPK1NR3C1REN | |
| SCHEMBL16720815 | 0.76 | NOS1 (0.42) | — | |
| SCHEMBL16719560 | 0.75 | PIK3CD (0.44) | AHR | |
| SCHEMBL6251056 | 0.75 | AHR (0.46) | AHRKEAP1PDPK1NR3C1REN | |
| SCHEMBL6669373 | 0.73 | CYP1A2 (0.45) | — | |
| SCHEMBL16719974 | 0.72 | AHR (0.40) | AHRKEAP1PDPK1NR3C1REN | |
| SCHEMBL2373481 | 0.72 | ALDH1A1 (0.44) | — | |
| SCHEMBL16720156 | 0.70 | BCAT1 (0.33) | BCHE | |
| SCHEMBL109665 | 0.69 | AHR (0.56) | AHRKEAP1PDPK1NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068758-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | The Wistar Institute Of Anatomy And Biology (US) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015073864-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | THE WISAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2015-05-21 | — | — | WO | disclosed |