Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.68 |
| ▸ | IKBKB | O14920 | 1/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 12/20 | 0.42 |
| ▸ | PGR | P06401 | 10/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.41 |
| ▸ | AR | P10275 | 4/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31492457 | 0.85 | AHR (0.60) | AHRNR3C1PGRKEAP1NR3C2 | |
| SCHEMBL443938 | 0.81 | AHR (1.00) | AHRIKBKBNR3C1PGRKEAP1 | |
| SCHEMBL4173132 | 0.78 | REN (0.49) | AHRNR3C1PGRKEAP1NR3C2 | |
| SCHEMBL27487512 | 0.77 | AHR (0.47) | AHRNR3C1PGRKEAP1NR3C2 | |
| SCHEMBL5659490 | 0.77 | AHR (0.47) | AHRNR3C1PGRKEAP1NR3C2 | |
| SCHEMBL594405 | 0.76 | AHR (0.50) | AHRIKBKBNR3C1PGRKEAP1 | |
| Indole SCHEMBL7216540 | 0.76 | AHR (0.78) | AHRKEAP1PDPK1TNFRIPK1 | |
| SCHEMBL10463771 | 0.74 | AHR (0.70) | AHRNR3C1PGRKEAP1NR3C2 | |
| SCHEMBL28756102 | 0.73 | DPP4 (0.46) | AHRNR3C1KEAP1PDPK1REN | |
| SCHEMBL5662296 | 0.73 | AHR (0.52) | AHRIKBKBNR3C1PGRNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030203959-A1 | Novel modulators of potassium channels | 4SC AG (DE) | 2003-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030203959-A1 | Novel modulators of potassium channels | HCN3, KCNN3, KCNN1 | AHR 379/4885IKBKB 1635/4885NR3C1 162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.