Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 17/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 11/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27487533 | 0.81 | PTGS2 (0.58) | PTGS2PTGS1 | |
| SCHEMBL27469593 | 0.81 | PTGS2 (0.55) | PTGS2PTGS1ITGB1ITGA4ITGB7 | |
| SCHEMBL27469590 | 0.79 | PTGS2 (0.58) | PTGS2PTGS1 | |
| SCHEMBL27487166 | 0.77 | PTGS2 (0.40) | PTGS2PTGS1ITGB1ITGA4ITGB7 | |
| SCHEMBL27489275 | 0.76 | PTGS2 (0.51) | PTGS2PTGS1 | |
| SCHEMBL27470571 | 0.75 | PTGS2 (0.40) | PTGS2PTGS1ITGB1ITGA4ITGB7 | |
| SCHEMBL27522830 | 0.75 | PTGS2 (0.46) | PTGS2PTGS1ITGB1ITGA4ITGB7 | |
| SCHEMBL27471097 | 0.75 | PTGS2 (0.43) | PTGS2PTGS1ITGB1ITGA4ITGB7 | |
| SCHEMBL27486815 | 0.74 | PTGS2 (0.44) | PTGS2PTGS1ITGB1ITGA4ITGB7 | |
| SCHEMBL27489264 | 0.72 | PTGS2 (0.42) | PTGS2PTGS1MEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1167687-C | Arylpyridazinones as prostaglandin endoperoxide H synthase biosynthesis inhibitors | ���Ͽع�����˾ | 2004-09-22 | — | — | CN | disclosed |