Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | EGFR | P00533 | 4/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5805590 | 0.89 | MAPT (0.52) | ALDH1A1MAPTL3MBTL1KDM4ENPC1 | |
| SCHEMBL7026711 | 0.86 | CYP1A2 (0.42) | CYP1A2CYP2C9CYP2C19ALDH1A1MAPT | |
| SCHEMBL7032110 | 0.82 | KDM4E (0.42) | CYP1A2CYP2C9CYP2C19ALDH1A1MAPT | |
| SCHEMBL12724361 | 0.80 | CYP1A2 (0.49) | CYP1A2CYP2C9CYP2C19ALDH1A1L3MBTL1 | |
| SCHEMBL14665300 | 0.79 | ALDH1A1 (0.44) | CYP1A2CYP2C9CYP2C19ALDH1A1MAPT | |
| SCHEMBL6024348 | 0.79 | EGFR (0.49) | ALDH1A1MAPTL3MBTL1EGFRKDM4E | |
| SCHEMBL2995499 | 0.77 | ALDH1A1 (0.53) | ALDH1A1MAPTL3MBTL1EGFRKDM4E | |
| Acridan SCHEMBL7755741 | 0.77 | HDAC4 (0.42) | CYP1A2CYP2C9CYP2C19L3MBTL1EGFR | |
| SCHEMBL38665307 | 0.76 | CYP1A2 (0.73) | CYP1A2CYP2C9CYP2C19L3MBTL1CYP3A4 | |
| SCHEMBL12724363 | 0.76 | CYP1A2 (0.73) | CYP1A2CYP2C9CYP2C19L3MBTL1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1312252-A | Intermediate of chemical compound generating chemical illumination when reacts with phosphatase | RUMIGEN CO (US) | 2001-09-12 | — | — | CN | disclosed |
| CN-1180349-A | Compounds, compositions and methods for generating chemiluminescence by reaction with phosphatases | LUMIGEN INC (US) | 1998-04-29 | — | — | CN | disclosed |