SCHEMBL2995499

SCHEMBL2995499

O=C(O)C1c2ccccc2Nc2ccccc21

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.53
EGFR P00533 4/20 0.47
MAPT P10636 9/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
IDO1 P14902 1/20 0.42
TDO2 P48775 1/20 0.42
KDM4E B2RXH2 4/20 0.42
TDP1 Q9NUW8 3/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
EDNRA P25101 1/20 0.41
GAA P10253 2/20 0.40
SRC P12931 1/20 0.40
NLRP3 Q96P20 1/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2986141 0.98 ALDH1A1 (0.51) ALDH1A1EGFRMAPTL3MBTL1IDO1
SCHEMBL1461839 0.86 MAPT (0.56) ALDH1A1MAPTL3MBTL1IDO1TDO2
SCHEMBL8136999 0.84 ALDH1A1 (0.47) ALDH1A1EGFRMAPTL3MBTL1IDO1
SCHEMBL13092132 0.82 MAPT (0.48) ALDH1A1EGFRMAPTL3MBTL1IDO1
SCHEMBL3855902 0.81 ALDH1A1 (0.45) ALDH1A1EGFRMAPTL3MBTL1KDM4E
SCHEMBL10355854 0.81 EDNRA (0.50) ALDH1A1EDNRAMEN1KMT2A
SCHEMBL11527593 0.81 EDNRA (0.50) ALDH1A1EDNRAMEN1KMT2A
SCHEMBL2986140 0.81 MAPT (0.44) ALDH1A1EGFRMAPTL3MBTL1IDO1
SCHEMBL27487537 0.77 CYP1A2 (0.46) ALDH1A1EGFRMAPTL3MBTL1IDO1
SCHEMBL6024348 0.76 EGFR (0.49) ALDH1A1EGFRMAPTL3MBTL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3494396-B1 CHEMILUMINESCENT AND FLUORESCENT SUBSTRATE PADS AND USES THEREOF PIERCE BIOTECHNOLOGY INC (US) 2025-06-11 EP claimed
EP-3494396-B1 CHEMILUMINESCENT AND FLUORESCENT SUBSTRATE PADS AND USES THEREOF PIERCE BIOTECHNOLOGY INC (US) 2025-06-11 EP disclosed
CN-116466091-A Kit for detecting IgA immune complex based on chemiluminescence method 深圳市陆为生物技术有限公司 2023-07-21 CN disclosed
US-11203573-B2 N-alkylation of acridans SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2021-12-21 US disclosed
US-20210230119-A1 N-ALKYLATION OF ACRIDANS SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2021-07-29 US disclosed
CN-104411688-B Synthesis of acridinium compounds from N-alkylation of 9,10-dihydroacridine 西门子医疗保健诊断公司 2019-01-08 CN disclosed
US-9533974-B2 Ultra-sensitive chemiluminescent substrates for enzymes and their conjugates MICHIGAN DIAGNOSTICS, LLC (US) 2017-01-03 US disclosed
US-20150031889-A1 ULTRA-SENSITIVE CHEMILUMINESCENT SUBSTRATES FOR ENZYMES AND THEIR CONJUGATES GIRI BRIJ PAL (US) 2015-01-29 US disclosed
US-8932881-B2 Ultra-sensitive chemiluminescent substrates for enzymes and their conjugates GIRI BRIJ PAL (US) 2015-01-13 US disclosed
CN-1659278-B Fluorescent detection of peroxidase enzymes LUMIGEN INC 2014-07-09 CN disclosed
US-6030803-A FOR USE AS SUBSTRATE IN PEROXIDASE ASSAYS; ALPHA-CARBON ATOM OF THE ESTER ALKYL GROUP IS AN ALIPHATIC CARBON ATOM DE STAAT DER NEDERLANDEN, VERTEGENWOORDIGD DOOR DE MINISTER VAN WELZIJN, VOLKSGESZONHEID EN CULTUUR (NL) 2000-02-29 US disclosed
US-6002000-A SPIRO-ACRIDAN DERIVATIVES DADE BEHRING MARBURG GMBH (DE) 1999-12-14 US disclosed
US-5936070-A SPIRO-ACRIDINE DYES DADE BEHRING MARBURG GMBH (DE) 1999-08-10 US disclosed
US-5672478-A MIXING SAMPLE, CHEMILUMINESCENT COMPOUND AND ACTIVATOR, THEN DETECTING AND MEASURING LUMINESCENCE WHICH INDICATES AMOUNT OF ANALYTE IN SAMPLE BEHRINGWERKE AG (DE) 1997-09-30 US disclosed
US-5545834-A USED AS LABELS FOR IMMUNOASSAY AND NUCLEIC ACID PROBE ASSAYS BEHRINGWERKE AG (DE) 1996-08-13 US disclosed
EP-0651752-A1 NOVEL CHEMILUMINESCENT COMPOUNDS AND METHODS OF USE BEHRINGWERKE AG (DE) 1995-05-10 EP disclosed
WO-1994002486-A1 NOVEL CHEMILUMINESCENT COMPOUNDS AND METHODS OF USE SYNTEX (U.S.A.) INC. (US) 1994-02-03 WO disclosed
US-4219432-A Stabilized amide-imide graft of ethylene copolymeric additives for lubricants EXXON RESEARCH & ENGINEERING CO. (US) 1980-08-26 US disclosed
EP-0000648-A1 Stabilised imide graft of ethylene copolymeric additives for lubricants, process for their preparation, process for stabilising additive concentrates for lubricants based on the imide graft ethylene copolymer and lubricating oil compositions comprising the stabilised additive EXXON RESEARCH AND ENGINEERING COMPANY (US) 1979-02-07 EP disclosed
US-4137185-A VISCOSITY INDEX IMPROVERS EXXON RESEARCH & ENGINEERING CO. (US) 1979-01-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210230119-A1 N-ALKYLATION OF ACRIDANS ACR, NCL, MGMT ALDH1A1 284/4885EGFR 1346/4885MAPT 4824/4885
US-20150031889-A1 ULTRA-SENSITIVE CHEMILUMINESCENT SUBSTRATES FOR ENZYMES AND THEIR CONJUGATES DUOX1, XDH, MPO ALDH1A1 69/4885EGFR 2197/4885MAPT 3345/4885
US-11203573-B2 N-alkylation of acridans ACR, NCL, MGMT ALDH1A1 284/4885EGFR 1346/4885MAPT 4824/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.