Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL68859 | 0.77 | ALDH1A1 (0.57) | S100A4SIGMAR1ALDH1A1KDM4EHPGD | |
| SCHEMBL8373688 | 0.77 | SIGMAR1 (0.43) | S100A4SIGMAR1ALDH1A1KDM4EHPGD | |
| SCHEMBL10814919 | 0.77 | SIGMAR1 (0.47) | S100A4SIGMAR1ALDH1A1KDM4EHPGD | |
| SCHEMBL8817667 | 0.77 | SMN1; SMN2 (0.56) | SIGMAR1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL28814207 | 0.77 | SIGMAR1 (0.43) | S100A4SIGMAR1ALDH1A1KDM4EHPGD | |
| SCHEMBL16585332 | 0.75 | SIGMAR1 (0.43) | S100A4SIGMAR1ALDH1A1KDM4EHPGD | |
| SCHEMBL10537641 | 0.74 | GSK3B (0.51) | SIGMAR1ALDH1A1KDM4EHSD17B10TSHR | |
| SCHEMBL2171598 | 0.73 | MAPT (0.50) | S100A4SIGMAR1ALDH1A1KDM4EHPGD | |
| SCHEMBL9635192 | 0.73 | CA12 (0.39) | S100A4SIGMAR1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL8474208 | 0.73 | SIGMAR1 (0.41) | S100A4SIGMAR1ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110698456-B | Synthesis method of 2, 3-dihydrothiochromen-4-one and derivatives thereof | 重庆医药高等专科学校 | 2021-05-14 | — | — | CN | disclosed |
| CN-110698456-A | Synthesis method of 2, 3-dihydrothiochromen-4-one and derivatives thereof | 重庆医药高等专科学校 | 2020-01-17 | — | — | CN | disclosed |
| CN-102453028-B | Antifungal agent-2- [ (2, 3-dihydro-4H-benzo [ b ] thiopyran-4-ylidene) hydrazono ] -4-oxotetrahydrothia (oxazole) -5-acetic acid derivative | UNIV SHENYANG PHARMACEUTICAL | 2014-07-30 | — | — | CN | disclosed |
| CN-101434595-B | Antifungal agent-thiochromanone condensed amino urea series | UNIV SHENYANG PHARMACEUTICAL | 2014-06-25 | — | — | CN | disclosed |
| CN-101434595-A | Antifungal agent-thiochromanone condensed amino urea series | UNIV SHENYANG PHARMACEUTICAL (CN) | 2009-05-20 | — | — | CN | disclosed |
| CN-1196696-C | New thiochromane derivatives and use as thrombin inhibitors | ASTRAZENECA AG (SE) | 2005-04-13 | — | — | CN | disclosed |
| CN-1441799-A | New thiochromane derivatives and use as thrombin inhibitors | ASTRAZENECA AG (SE) | 2003-09-10 | — | — | CN | disclosed |