SCHEMBL27488790

SCHEMBL27488790

Cc1nc(N2[CH]SC=C2)sc1C

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2496995 0.64 NOS1 (0.38) NOS1
SCHEMBL27696174 0.60 NOS1 (0.34) NOS1
SCHEMBL14196470 0.59 ALDH1A1 (0.41) NOS1
SCHEMBL20062956 0.59 ALDH1A1 (0.40) NOS1
SCHEMBL4852520 0.59 ALDH1A1 (0.61)
Bromide SCHEMBL9486332 0.58 NOS1 (0.32) NOS1
SCHEMBL20071965 0.58 USP2 (0.41) NOS1
Bromide SCHEMBL9486340 0.57 NOS1 (0.31) NOS1
SCHEMBL2825385 0.57 DPP4 (0.42)
SCHEMBL4850658 0.57 PIK3CD (0.61)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1210307-C Humanized anti-CD 20 monoclonal antibody ZHONGXIN GUOJIAN PHARMACEUTICA (CN) 2005-07-13 CN disclosed
CN-1420129-A Humanized anti-CD 20 monoclonal antibody ZHONGXIN GUOJIAN PHARMACEUTICA (CN) 2003-05-28 CN disclosed