SCHEMBL27489014

SCHEMBL27489014

NNC(=O)N(N)c1ncnc(OCc2ccccc2)n1

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.40
ALDH1A1 P00352 2/20 0.40
ACACB O00763 2/20 0.38
P4HTM Q9NXG6 1/20 0.37
NPC1 O15118 2/20 0.36
EGFR P00533 1/20 0.36
ERBB2 P04626 1/20 0.36
PARP10 Q53GL7 1/20 0.36
LTA4H P09960 1/20 0.36
GAA P10253 1/20 0.36
PIN1 Q13526 1/20 0.36
MAP3K7 O43318 1/20 0.35
TAB1 Q15750 1/20 0.35
ALOX5 P09917 1/20 0.35
RAB9A P51151 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28751868 0.75 ACACB (0.42) MAPTALDH1A1ACACBNPC1EGFR
SCHEMBL27461055 0.75 MEN1 (0.37) MAPTALDH1A1NPC1GAARAB9A
SCHEMBL27771143 0.74 PIN1 (0.57) ALDH1A1NPC1PIN1RAB9A
SCHEMBL28122016 0.74 MEN1 (0.33) ACACBMAP3K7TAB1
SCHEMBL27599363 0.73 ALOX5 (0.45) MAPTALDH1A1P4HTMPARP10ALOX5
SCHEMBL27617777 0.73 ALDH1A1 (0.41) MAPTALDH1A1NPC1EGFRERBB2
SCHEMBL27884312 0.72 KDM4E (0.33) ALDH1A1
SCHEMBL28091717 0.69 KDM4E (0.32) ALDH1A1
SCHEMBL27730833 0.69 ALOX5 (0.46) ACACBP4HTMEGFRPARP10LTA4H
SCHEMBL28093088 0.68 NPC1 (0.45) MAPTALDH1A1NPC1PARP10RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101380297-A Compound platinum medicine sustained-release agent JINAN SHUAIHUA PHARMACEUTICAL (CN) 2009-03-11 CN claimed
CN-101254170-A An anticancer sustained release injection carrying clorfarabine and its synergist JINAN KANGQUAN PHARMACEUTICAL (CN) 2008-09-03 CN claimed
CN-101244034-A Sustained-release agent containing taxone and its synergistic agent JINAN KANGQUAN PHARMACEUTICAL (CN) 2008-08-20 CN claimed
CN-101023922-A Anti-cancer sustained-release agent carrying glucocorticoid hormone and chemotherapeutic drug KANGQUAN MEDICINE SCIENCE TECH (CN) 2007-08-29 CN claimed
CN-101002730-A Compounding anticarcinogen containing neovascular-inhibitor SHUAIHUA MEDICAL TECH CO LTD J (CN) 2007-07-25 CN claimed
CN-1973823-A Anticancer composition containing Synergist SHANDONG LANJIN BIOENGINEERING (CN) 2007-06-06 CN claimed
CN-1969816-A Anticancer sustained-release agent containing epothilone JINAN SHUAIHUA MEDICAL TECHNOL (CN) 2007-05-30 CN claimed
CN-1957910-A Anti cancer controlled release formulation of containing consubstantial hydrolytic agent LANJIN BIOENGINEERING CO LTD S (CN) 2007-05-09 CN claimed
CN-1927174-A Anticancer slow release injection loading tetrazole violet and potentiating agent thereof JINAN SHUAIHUA PHARMACEUTICAL (CN) 2007-03-14 CN claimed
CN-1923171-A Compound recipe anti-cancer drugs slow release agent comprising anticancer antibiotics and booster thereof JINAN KANGQUAN PHARMACEUTICAL (CN) 2007-03-07 CN claimed
CN-1875934-A Anticancer drug sustained-release injection carrying clorfarabine and synergist thereof JINAN KANGQUAN PHARMACEUTICAL (CN) 2006-12-13 CN claimed
CN-1861050-A Anticancer drug sustained-release injection loaded with platinum compound and synergist thereof LANJIN BIOENGINEERING CO LTD S (CN) 2006-11-15 CN claimed
CN-1861047-A Slow-releasing injection contg. vasoinhibitor and potentiator type anticarcinogen SHUAIHUA MEDICINE SCIENCE AND (CN) 2006-11-15 CN claimed
CN-1861049-A Anticancer drug sustained-release injection containing gemcitabine LANJIN BIOENGINEERING CO LTD S (CN) 2006-11-15 CN claimed
CN-1850039-A Compound platinum medicine slow-release agent SHUAIHUA MEDICINE SCIENCE TECH (CN) 2006-10-25 CN claimed
CN-1846679-A Sustained-release injection containing methotrexate and synergist thereof JINAN SHUAIHUA MEDICINE SCI TE (CN) 2006-10-18 CN claimed
CN-1846676-A Sustained-release injection containing fluorouracil synergist and preparation method thereof JINAN SHUAIHUA MEDICINE SCI TE (CN) 2006-10-18 CN claimed
CN-1846673-A Slow-released anticancer medicine prepn containing pyrimidine medicine JINAN SHUAIHUA MEDICINE SCI TE (CN) 2006-10-18 CN claimed
CN-1846687-A Slow-release agent containing taxane and synergist thereof JINAN KANGQUAN MEDICINE SCI TE (CN) 2006-10-18 CN claimed
CN-1628853-A Anti-cancer medicine composition KONG QINGZHONG (CN) 2005-06-22 CN claimed