Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | ACACB | O00763 | 2/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2777205 | 0.83 | TSHR (0.46) | ALOX5HTTMAOBLTA4HSMN1; SMN2 | |
| SCHEMBL27676967 | 0.78 | LMNA (0.41) | ALOX5PARP10NR4A1NR4A2NR4A3 | |
| SCHEMBL27599363 | 0.75 | ALOX5 (0.45) | ALOX5PARP10NR4A1NR4A2NR4A3 | |
| SCHEMBL27641915 | 0.74 | PIN1 (0.52) | PARP10HTTKMT2AMEN1 | |
| SCHEMBL28146880 | 0.72 | MKNK1 (0.40) | KMT2AMEN1SMN1; SMN2 | |
| Diphenylmethane SCHEMBL27436307 | 0.70 | PLA2G10 (0.61) | ALOX5KMT2AMEN1LTA4HSMN1; SMN2 | |
| SCHEMBL32682868 | 0.69 | NR4A2 (0.59) | PARP10ACACBNR4A1NR4A2NR4A3 | |
| SCHEMBL2779108 | 0.68 | LTA4H (0.55) | ALOX5MAOBLTA4HSMN1; SMN2 | |
| Diphenylmethane SCHEMBL28159499 | 0.68 | PLA2G10 (0.53) | ALOX5 | |
| SCHEMBL19607728 | 0.68 | TDP1 (0.58) | KMT2AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101254166-A | An anticancer sustained release injection carrying clorfarabine and its synergist | JINAN KANGQUAN PHARMACEUTICAL (CN) | 2008-09-03 | — | — | CN | disclosed |