Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | DDX3X | O00571 | 2/20 | 0.57 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.56 |
| ▸ | ITGAV | P06756 | 2/20 | 0.56 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.56 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1275926 | 0.84 | RAB9A (0.75) | NPC1RAB9APOLBHPGDALDH1A1 | |
| SCHEMBL5402239 | 0.81 | EGFR (0.58) | NPC1RAB9APOLBHPGDALDH1A1 | |
| SCHEMBL7748013 | 0.79 | NPC1 (0.54) | NPC1RAB9APOLBHPGDMAPT | |
| SCHEMBL23615555 | 0.79 | SLC1A3 (0.53) | RAB9APOLBALDH1A1DDX3XITGB3 | |
| SCHEMBL8369698 | 0.79 | ALDH1A1 (0.76) | NPC1RAB9APOLBHPGDALDH1A1 | |
| SCHEMBL27599875 | 0.78 | CYP1A2 (0.59) | NPC1RAB9APOLBHPGDALDH1A1 | |
| SCHEMBL27582499 | 0.77 | ALDH1A1 (0.62) | NPC1RAB9APOLBHPGDALDH1A1 | |
| SCHEMBL23615733 | 0.77 | MEN1 (0.43) | NPC1RAB9APOLBALDH1A1DDX3X | |
| SCHEMBL8421705 | 0.77 | RAB9A (0.64) | NPC1RAB9APOLBHPGDALDH1A1 | |
| SCHEMBL8334833 | 0.77 | RAB9A (0.64) | NPC1RAB9APOLBHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1164232-A | Aminoheterocyclic derivatives as antithrombotic or anticoagulant agents | ZENECA LTD (GB) | 1997-11-05 | — | — | CN | disclosed |