Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TGM2 | P21980 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | GSR | P00390 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL1311763 | 0.86 | LMNA (0.56) | AKT1ALDH1A1TGM2TP53MAPT | |
| Biphenyl SCHEMBL36309 | 0.86 | LMNA (0.56) | AKT1ALDH1A1TGM2TP53MAPT | |
| Biphenyl SCHEMBL22032284 | 0.82 | LMNA (0.50) | AKT1ALDH1A1TGM2TP53MAPT | |
| Biphenyl SCHEMBL27428185 | 0.82 | ALDH1A1 (0.55) | AKT1ALDH1A1TGM2TP53MAPT | |
| Biphenyl SCHEMBL7005540 | 0.82 | TSHR (0.55) | AKT1ALDH1A1TGM2TP53MAPT | |
| Biphenyl SCHEMBL1539344 | 0.82 | TSHR (0.55) | AKT1ALDH1A1TGM2TP53MAPT | |
| Phenol SCHEMBL2135422 | 0.82 | CA12 (0.55) | AKT1ALDH1A1TGM2MAPTSMN1; SMN2 | |
| Styrene SCHEMBL6386510 | 0.80 | ALDH1A1 (0.67) | AKT1ALDH1A1TGM2TP53MAPT | |
| Aniline SCHEMBL27409704 | 0.80 | TSHR (0.52) | AKT1ALDH1A1TGM2MAPTSMN1; SMN2 | |
| Biphenyl SCHEMBL27490389 | 0.80 | AKT1 (0.48) | AKT1ALDH1A1TGM2TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885869-A1 | THERAPEUTIC AGENT FOR DIABETES | Japan Tobacco Inc. (JP) | 1998-12-23 | — | — | EP | disclosed |