Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | PRCP | P42785 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9453770 | 0.82 | SIGMAR1 (0.47) | SIGMAR1CYP11B2ADRA1AGID4KDM1A | |
| SCHEMBL503849 | 0.81 | SIGMAR1 (0.62) | SIGMAR1CYP11B2ADRA1AGID4KDM1A | |
| SCHEMBL29390302 | 0.81 | SIGMAR1 (0.62) | SIGMAR1CYP11B2ADRA1AGID4KDM1A | |
| SCHEMBL28025940 | 0.80 | SIGMAR1 (0.60) | SIGMAR1CYP11B2ADRA1AGID4KDM1A | |
| SCHEMBL30606845 | 0.80 | SIGMAR1 (0.60) | SIGMAR1CYP11B2ADRA1AGID4KDM1A | |
| Ammonia Solution, Strong SCHEMBL8210515 | 0.80 | SIGMAR1 (0.60) | SIGMAR1CYP11B2ADRA1AGID4KDM1A | |
| SCHEMBL8765982 | 0.79 | PDGFRA (0.45) | SIGMAR1CYP11B2KDM1AMAOAMAOB | |
| Bicarbonate SCHEMBL376797 | 0.75 | SIGMAR1 (0.55) | SIGMAR1CYP11B2ADRA1AKDM1AMAOA | |
| SCHEMBL4795332 | 0.74 | ADRA1A (0.44) | SIGMAR1CYP11B2ADRA1ATAAR1IDO1 | |
| Phenol SCHEMBL7789542 | 0.74 | SIGMAR1 (0.54) | SIGMAR1CYP11B2ADRA1AKDM1AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1212705-A | Serine protease inhibitors | AKZO NOBEL NV (NL) | 1999-03-31 | — | — | CN | disclosed |