Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 3/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8967058 | 0.90 | ADRA2A (0.47) | ADRA1AIDO1TAAR1ADRA2AADRA1D | |
| SCHEMBL4278950 | 0.75 | ADRA1A (0.51) | ADRA1AIDO1PDPK1SIGMAR1TAAR1 | |
| SCHEMBL4276600 | 0.73 | ADRA1A (0.40) | ADRA1AIDO1PDPK1SIGMAR1CYP2D6 | |
| SCHEMBL4276972 | 0.73 | ADRA1A (0.40) | ADRA1AIDO1PDPK1SIGMAR1CYP11B2 | |
| SCHEMBL4275619 | 0.73 | PIN1 (0.43) | ADRA1AIDO1PDPK1SIGMAR1CYP11B2 | |
| SCHEMBL9453770 | 0.73 | SIGMAR1 (0.47) | ADRA1AIDO1PDPK1SIGMAR1TAAR1 | |
| SCHEMBL8189288 | 0.72 | ADRA1A (0.49) | ADRA1AIDO1PDPK1SIGMAR1TAAR1 | |
| SCHEMBL3140174 | 0.72 | PRCP (0.57) | TAAR1HTR2A | |
| SCHEMBL5680358 | 0.72 | ADRA1A (0.39) | ADRA1AIDO1PDPK1SIGMAR1TAAR1 | |
| SCHEMBL1504258 | 0.71 | ADRA1A (0.41) | ADRA1AIDO1PDPK1SIGMAR1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1556807-A | Chemical compounds | �㶫��������ҽҩ�ɷ�����˾ | 2004-12-22 | — | — | CN | claimed |
| US-7414048-B2 | 4,5-dihydro-isoxazole derivatives and their pharmaceutical use | JANSSEN PHARMACEUTICA, N.V. (BE) | 2008-08-19 | — | — | US | disclosed |
| US-6583141-B1 | T cell mediated rheumatic diseases | JANSSEN PHARMACEUTICA, N.V. (BE) | 2003-06-24 | — | — | US | disclosed |
| EP-0805796-A1 | CELL ADHESION INHIBITORS | BIOGEN, INC. (US) | 1997-11-12 | — | — | EP | disclosed |
| WO-1996022966-A1 | CELL ADHESION INHIBITORS | BIOGEN, INC. (US) | 1996-08-01 | — | — | WO | disclosed |
| US-3966624-A | LUBRICANTS | SUN OIL COMPANY OF PENNSYLVANIA (US) | 1976-06-29 | — | — | US | disclosed |