Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 10/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27512079 | 0.80 | KDM4E (0.33) | ALDH1A1KDM4EMEN1HPGDKMT2A | |
| SCHEMBL27548316 | 0.77 | ALDH1A1 (0.53) | ALDH1A1CYP3A4HSD17B10TDP1KDM4E | |
| SCHEMBL8024917 | 0.75 | ALDH1A1 (0.56) | PGRALDH1A1CYP3A4HSD17B10TDP1 | |
| SCHEMBL3228471 | 0.73 | PGR (0.41) | PGRALDH1A1CYP3A4HSD17B10TDP1 | |
| SCHEMBL27512077 | 0.70 | KIF11 (0.34) | ALDH1A1KDM4EMEN1HPGDKMT2A | |
| SCHEMBL28840503 | 0.70 | KIF11 (0.47) | ALDH1A1KIF11 | |
| SCHEMBL27591711 | 0.67 | ALDH1A1 (0.52) | ALDH1A1CYP3A4HSD17B10TDP1KDM4E | |
| SCHEMBL28159978 | 0.64 | KIF11 (0.42) | ALDH1A1TDP1KDM4EMEN1HPGD | |
| SCHEMBL27343325 | 0.63 | KIF11 (0.45) | ALDH1A1HSD17B10TDP1KDM4EMEN1 | |
| SCHEMBL27722494 | 0.63 | KIF11 (0.45) | KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1626534-A | Steroid receptor modulator compounds and methods | LIGAND PHARM INC (US) | 2005-06-15 | — | — | CN | disclosed |
| CN-1172917-C | Steroid receptor modulator compounds and methods | ��λ��ҩ��ɷ�����˾ | 2004-10-27 | — | — | CN | disclosed |
| CN-1175247-A | Steroid receptor modulator compounds and methods | LIGAND PHARM INC (US) | 1998-03-04 | — | — | CN | disclosed |