Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 10/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 10/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GPX4 | P36969 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19665946 | 0.77 | NPC1 (0.44) | MTNR1AMTNR1BTRPV1ALDH1A1NPC1 | |
| SCHEMBL19665956 | 0.77 | NPC1 (0.44) | MTNR1AMTNR1BTRPV1ALDH1A1NPC1 | |
| SCHEMBL15928727 | 0.76 | TSHR (0.44) | MTNR1AMTNR1BMAPTGRIN2DGRIN3B | |
| SCHEMBL14818792 | 0.76 | ALDH1A1 (0.55) | MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL5287179 | 0.73 | PPARA (0.45) | TRPV1ALDH1A1NPC1TP53GPX4 | |
| SCHEMBL16486913 | 0.72 | MTNR1A (0.57) | MTNR1AMTNR1B | |
| SCHEMBL12090629 | 0.72 | HTR7 (0.53) | MTNR1AMTNR1BMAPTALDH1A1NPC1 | |
| SCHEMBL14034634 | 0.72 | KCNN4 (0.50) | MAPT | |
| SCHEMBL25751951 | 0.72 | SIGMAR1 (0.58) | MAPTSIGMAR1 | |
| SCHEMBL214884 | 0.72 | ALDH1A1 (0.59) | ALDH1A1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1171394-A | New urea derivatives, their preparation and their therapeutic and prophylactic use | SANKYO CO (JP) | 1998-01-28 | — | — | CN | disclosed |