Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SOD1 | P00441 | 1/20 | 0.32 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL188333 | 0.80 | THRB (0.42) | CYP4F2CYP4A11CES2CES1ERN1 | |
| SCHEMBL21810570 | 0.78 | CYP4F2 (0.47) | CYP4F2CYP4A11CES2CES1ERN1 | |
| SCHEMBL3976540 | 0.77 | KMT2A (0.50) | CES2CES1CA1KMT2A | |
| SCHEMBL18697338 | 0.76 | CYP4F2 (0.46) | CYP4F2CYP4A11CES2CES1ERN1 | |
| SCHEMBL4803849 | 0.74 | CYP4F2 (0.44) | CYP4F2CYP4A11CES2CES1ERN1 | |
| SCHEMBL1995396 | 0.74 | CYP4F2 (0.69) | CYP4F2CYP4A11CES2CES1BACE1 | |
| SCHEMBL442239 | 0.74 | MEN1 (0.52) | CYP4F2CYP4A11CES2CES1CA12 | |
| SCHEMBL1079532 | 0.73 | CYP4F2 (0.41) | CYP4F2CYP4A11 | |
| SCHEMBL29220639 | 0.73 | MEN1 (0.44) | ERN1MAPTKMT2A | |
| SCHEMBL15763925 | 0.73 | CYP4F2 (0.47) | CYP4F2CYP4A11CES2CES1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1616432-A | Compound,its use and pharmaceutical compositions comprising same | ELAN PHARM INC (US) | 2005-05-18 | — | — | CN | disclosed |
| CN-1171878-C | Compounds, their use and pharmaceutical compositions containing them | ������˹ҩƷ��˾ | 2004-10-20 | — | — | CN | disclosed |
| CN-1253554-A | Heterocyclic compounds and their use for inhibiting 'beta'-amyloid peptide | ELAN MEDICINE CO (US) | 2000-05-17 | — | — | CN | disclosed |
| CN-1242007-A | Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising such compounds, and methods of inhibiting beta amyloid peptide release and/or its synthesis using such compounds | ELAND PHARMACEUTICAL CORP (US) | 2000-01-19 | — | — | CN | disclosed |