Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.42 |
| ▸ | MPO | P05164 | 8/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27524772 | 0.90 | GPR84 (0.42) | HTR2AHTR2CGPR84HTR2BHTR1A | |
| SCHEMBL28749184 | 0.81 | TSHR (0.48) | HTR2AHTR2CGPR84MPOHTR2B | |
| SCHEMBL5791452 | 0.80 | TSHR (0.56) | HTR2AHTR2CGPR84MPOHTR2B | |
| SCHEMBL5791726 | 0.80 | TSHR (0.56) | HTR2AHTR2CGPR84MPOHTR2B | |
| SCHEMBL5793488 | 0.80 | TSHR (0.56) | HTR2AHTR2CGPR84MPOHTR2B | |
| SCHEMBL27509165 | 0.79 | MPO (0.41) | HTR2AHTR2CMPOTSHRMTNR1A | |
| SCHEMBL27509545 | 0.79 | MPO (0.38) | HTR2AHTR2CGPR84MPOSLC6A4 | |
| SCHEMBL8493464 | 0.78 | HTR2A (0.55) | HTR2AHTR2CGPR84MPOHTR2B | |
| SCHEMBL5794289 | 0.77 | HTR2A (0.54) | HTR2AHTR2CGPR84MPOHTR2B | |
| SCHEMBL5794797 | 0.77 | HTR2A (0.54) | HTR2AHTR2CGPR84MPOHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1223650-A | Piperidines and pyrrolidines | MERCK PATENT GMBH (DE) | 1999-07-21 | — | — | CN | disclosed |