Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 8/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27495705 | 0.90 | HTR2A (0.45) | GPR84HTR2AHTR2CHTR1AHTR2B | |
| SCHEMBL27495704 | 0.79 | TDO2 (0.44) | TDO2NR3C1MEN1KMT2A | |
| SCHEMBL27511350 | 0.79 | TDO2 (0.37) | GPR84TDO2HTR2AHTR2CNR3C1 | |
| SCHEMBL6469180 | 0.76 | HTR2A (0.62) | GPR84TDO2HTR2AHTR2CHTR1A | |
| Hydrochloric Acid SCHEMBL21546051 | 0.75 | HTR2A (0.60) | GPR84TDO2HTR2AHTR2CHTR1A | |
| SCHEMBL27510950 | 0.75 | TDO2 (0.42) | TDO2 | |
| SCHEMBL27495316 | 0.74 | TDO2 (0.42) | TDO2 | |
| SCHEMBL12950449 | 0.74 | GPR84 (0.53) | GPR84TDO2HTR2AHTR2CHTR1A | |
| SCHEMBL31158762 | 0.74 | GPR84 (0.53) | GPR84TDO2HTR2AHTR2CHTR1A | |
| SCHEMBL21562565 | 0.72 | TDO2 (0.41) | GPR84TDO2HTR2AHTR2CNR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1223650-A | Piperidines and pyrrolidines | MERCK PATENT GMBH (DE) | 1999-07-21 | — | — | CN | disclosed |