Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 8/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 2/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | GUSB | P08236 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27511350 | 0.92 | TDO2 (0.37) | HTR2AHTR2CMAPTSMN1; SMN2NR3C1 | |
| SCHEMBL27532210 | 0.90 | SNCA (0.41) | MAPTSMN1; SMN2SLC6A4NR3C1SNCA | |
| SCHEMBL27495318 | 0.84 | GUSB (0.39) | MAPTSMN1; SMN2SLC6A4NR3C1SNCA | |
| SCHEMBL27494526 | 0.83 | ALDH1A1 (0.42) | MPOHTR2AHTR2CMAPTMTNR1A | |
| SCHEMBL27557418 | 0.79 | HTT (0.43) | HTR2CSLC6A4 | |
| SCHEMBL27495705 | 0.79 | HTR2A (0.45) | MPOHTR2AHTR2CMTNR1AMTNR1B | |
| SCHEMBL27509165 | 0.76 | MPO (0.41) | MPOHTR2AHTR2CMAPTMTNR1A | |
| SCHEMBL27510950 | 0.75 | TDO2 (0.42) | MAPT | |
| SCHEMBL28749184 | 0.73 | TSHR (0.48) | MPOHTR2AHTR2CMTNR1AMTNR1B | |
| SCHEMBL5791452 | 0.72 | TSHR (0.56) | MPOHTR2AHTR2CMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1223650-A | Piperidines and pyrrolidines | MERCK PATENT GMBH (DE) | 1999-07-21 | — | — | CN | disclosed |